Endomysial Antibody IgA IFA Test: Comprehensive Celiac Disease Diagnosis
Understanding the Endomysial Antibody IgA IFA Test
The Endomysial Antibody IgA IFA Test represents a cornerstone in autoimmune gastrointestinal diagnostics, specifically designed to detect celiac disease with exceptional accuracy. This sophisticated immunofluorescence assay identifies immunoglobulin A (IgA) antibodies that target the endomysium—the connective tissue surrounding smooth muscle fibers in the small intestine. When individuals with genetic predisposition consume gluten, their immune system mistakenly attacks this tissue, leading to the characteristic intestinal damage seen in celiac disease.
What Does This Test Measure?
The Endomysial Antibody IgA IFA Test specifically detects:
- IgA class autoantibodies directed against endomysial antigens
- Autoimmune response to tissue transglutaminase (tTG) enzyme
- Immune system activation in response to gluten exposure
- Specific markers indicating active celiac disease
Who Should Consider This Test?
This specialized diagnostic test is recommended for individuals experiencing:
- Persistent gastrointestinal symptoms including chronic diarrhea, abdominal pain, and bloating
- Unexplained weight loss or failure to thrive in children
- Iron-deficiency anemia that doesn’t respond to treatment
- Dermatitis herpetiformis (skin rash associated with celiac disease)
- Family history of celiac disease or autoimmune disorders
- Unexplained elevated liver enzymes
- Neurological symptoms like peripheral neuropathy or ataxia
- Dental enamel defects or recurrent mouth ulcers
Clinical Benefits of Endomysial Antibody Testing
Choosing the Endomysial Antibody IgA IFA Test provides numerous advantages:
- High Diagnostic Specificity: This test offers over 99% specificity for celiac disease, making it one of the most reliable diagnostic tools available
- Early Detection: Identifies celiac disease before severe intestinal damage occurs
- Treatment Guidance: Results help guide implementation of gluten-free dietary management
- Disease Monitoring: Can be used to monitor treatment response and dietary compliance
- Comprehensive Assessment: Part of a complete celiac disease diagnostic panel
Understanding Your Test Results
Positive Result Interpretation
A positive Endomysial Antibody IgA IFA test strongly suggests active celiac disease. This typically indicates:
- Ongoing immune response to gluten consumption
- Probable intestinal mucosal damage
- Need for confirmatory intestinal biopsy in many cases
- Recommendation for strict gluten-free diet implementation
Negative Result Interpretation
A negative result generally indicates:
- Low probability of active celiac disease
- Possible need for additional testing if clinical suspicion remains high
- Consideration of selective IgA deficiency in rare cases
- Potential exploration of other gastrointestinal disorders
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Endomysial Antibody IgA IFA Test | $50 USD | $56 USD |
Testing Process Details
Turnaround Time: Sample collected daily by 11 AM; Same-day results available
Sample Requirements: 2 mL (1 mL minimum) serum from 1 SST tube
Shipping Instructions: Ship refrigerated or frozen
Pre-test Preparation: Overnight fasting is preferred for optimal results
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Control of Your Digestive Health Today
Don’t let unexplained gastrointestinal symptoms compromise your quality of life. The Endomysial Antibody IgA IFA Test provides the clarity needed for accurate celiac disease diagnosis and effective management. Our specialized immunopathology department, staffed by experienced gastroenterology specialists, ensures you receive the highest standard of diagnostic care.
Ready to get answers? Book your Endomysial Antibody IgA IFA Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward better digestive health and comprehensive celiac disease management.
