Cortisone Serum Test – Comprehensive Adrenal Function Assessment
Understanding Cortisone Serum Testing
The Cortisone Serum Test represents a sophisticated diagnostic approach to evaluating adrenal gland function and cortisol metabolism within your endocrine system. This specialized blood test measures circulating cortisone levels, providing clinicians with essential data about your body’s stress response system and hormonal balance. Cortisone serves as the inactive precursor to cortisol, and its measurement offers unique insights into adrenal health that complement traditional cortisol testing.
What the Cortisone Serum Test Measures
This advanced diagnostic assessment specifically detects and quantifies:
- Circulating cortisone levels in blood serum
- Adrenal cortex function and cortisol production capacity
- 11-beta-hydroxysteroid dehydrogenase enzyme activity
- Cortisol to cortisone conversion efficiency
- Overall adrenal gland health and stress response capability
Advanced LC-MS/MS Methodology
Our Cortisone Serum Test employs Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), the gold standard for steroid hormone analysis. This cutting-edge technology ensures:
- Exceptional accuracy and precision in measurement
- Minimal cross-reactivity with similar compounds
- Superior sensitivity for detecting subtle hormonal changes
- Reliable results for clinical decision-making
Who Should Consider Cortisone Serum Testing
This test is particularly valuable for individuals experiencing:
- Unexplained chronic fatigue and low energy levels
- Significant weight changes without dietary alterations
- Blood pressure fluctuations and cardiovascular symptoms
- Mood disorders including anxiety, depression, or irritability
- Sleep disturbances and circadian rhythm abnormalities
- Muscle weakness and decreased exercise tolerance
- Skin changes including thinning, bruising, or stretch marks
- Blood sugar regulation issues and metabolic concerns
Clinical Indications for Testing
Healthcare providers typically recommend Cortisone Serum testing when evaluating:
- Suspected adrenal insufficiency (Addison’s disease)
- Possible Cushing’s syndrome or cortisol excess
- Adrenal tumors or hyperplasia
- Pituitary gland disorders affecting ACTH production
- Monitoring adrenal function during steroid therapy
- Evaluating unexplained metabolic syndrome components
Benefits of Cortisone Serum Testing
Choosing our comprehensive Cortisone Serum assessment provides multiple advantages:
- Early Detection: Identifies adrenal dysfunction before severe symptoms develop
- Precise Diagnosis: Differentiates between various adrenal disorders
- Treatment Guidance: Informs appropriate therapeutic interventions
- Monitoring Capability: Tracks treatment effectiveness over time
- Comprehensive Evaluation: Provides broader adrenal function assessment than cortisol alone
- Preventive Health: Helps maintain optimal endocrine system function
Understanding Your Test Results
Interpreting Cortisone Serum levels requires professional medical expertise, but general guidance includes:
Normal Results
Normal cortisone levels typically indicate healthy adrenal function and proper cortisol metabolism. Your healthcare provider will consider your specific reference range based on age, gender, and testing time.
Elevated Levels
Higher than normal cortisone concentrations may suggest:
- Impaired conversion to active cortisol
- 11-beta-hydroxysteroid dehydrogenase deficiency
- Certain medication effects
- Specific adrenal or metabolic conditions
Reduced Levels
Lower than expected cortisone measurements might indicate:
- Adrenal insufficiency or fatigue
- Reduced adrenal cortisol production
- Pituitary gland dysfunction
- Chronic stress impact on adrenal reserves
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $74 |
| Regular Price | $82 |
Testing Schedule and Turnaround
Our efficient testing process ensures:
- Sample Collection: Monday or Thursday by 9:00 AM
- Report Availability: Wednesday or Saturday following collection
- Sample Requirements: 2 mL serum from Red Top tube (no gel barrier)
- Timing: Collect between 8:00-10:00 AM or 4:00-6:00 PM
- Preparation: Overnight fasting preferred
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and Illinois metropolitan area
- Houston and Texas Gulf Coast
- Phoenix and Arizona communities
- Philadelphia and Pennsylvania regions
- Additional locations nationwide
Take Control of Your Endocrine Health
Don’t let unexplained symptoms compromise your quality of life. Our Cortisone Serum Test provides the comprehensive adrenal assessment you need for accurate diagnosis and effective treatment planning. With our advanced LC-MS/MS technology and experienced endocrinology specialists, you receive reliable results and professional interpretation.
Ready to understand your adrenal health? Contact us today to schedule your Cortisone Serum Test:
Phone: +1(267) 388-9828
Our dedicated team is available to answer your questions, explain the testing process, and help you book your appointment at a convenient location near you.

