NNT Gene Glucocorticoid Deficiency Type 4 with or without Mineralocorticoid Deficiency NGS Genetic DNA Test
Comprehensive Genetic Testing for Adrenal Disorders
The NNT Gene Glucocorticoid Deficiency Type 4 NGS Genetic DNA Test represents a breakthrough in diagnostic precision for adrenal insufficiency conditions. This advanced genetic test specifically targets mutations in the NNT (nicotinamide nucleotide transhydrogenase) gene, which plays a crucial role in mitochondrial function and adrenal steroid hormone production. When this gene malfunctions, it can lead to severe hormonal imbalances affecting multiple body systems.
What Does This Test Measure?
This sophisticated genetic analysis utilizes Next-Generation Sequencing (NGS) technology to comprehensively examine the NNT gene for pathogenic variants. The test specifically detects:
- Point mutations and small insertions/deletions in the NNT gene
- Genetic variations associated with glucocorticoid deficiency type 4
- Mutations that may cause combined glucocorticoid and mineralocorticoid deficiency
- Inheritance patterns and carrier status information
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Unexplained fatigue, weakness, or chronic exhaustion
- Recurrent episodes of hypoglycemia (low blood sugar)
- Electrolyte imbalances and salt cravings
- Poor weight gain or failure to thrive in children
- Family history of adrenal insufficiency or endocrine disorders
- Unexplained hyperpigmentation of skin
- History of adrenal crises or stress-induced collapse
Clinical Benefits of Genetic Testing
Undergoing the NNT gene test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out genetic causes of adrenal insufficiency
- Personalized Treatment: Enables targeted hormone replacement therapy
- Family Planning: Provides crucial information for genetic counseling
- Early Intervention: Allows proactive management before severe symptoms develop
- Comprehensive Care: Guides multidisciplinary treatment involving endocrinology, nephrology, and hepatology specialists
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and medical specialists:
- Positive Result: Indicates the presence of pathogenic NNT gene mutations, confirming genetic predisposition to adrenal insufficiency
- Negative Result: Suggests no detectable mutations in the NNT gene, though other genetic or acquired causes should be considered
- Variant of Uncertain Significance: Some genetic changes may require additional family studies for proper interpretation
- Carrier Status: Identifies individuals who carry one copy of a mutated gene but may not show symptoms
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | NNT Gene Glucocorticoid Deficiency Type 4 with or without Mineralocorticoid Deficiency NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality testing regardless of your location.
Take Control of Your Health Today
Don’t let unexplained symptoms compromise your quality of life. Our comprehensive genetic testing provides the answers you need for proper diagnosis and effective treatment. Our team of genetic counselors and medical specialists are ready to guide you through the testing process and help interpret your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic health.
Early genetic diagnosis can significantly improve treatment outcomes and quality of life for individuals with adrenal insufficiency disorders. Trust our expertise in genetic testing to provide the clarity and guidance you need for better health management.