CORO1A Gene Immunodeficiency Type 8 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Immune System Disorders
The CORO1A Gene Immunodeficiency Type 8 NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for rare primary immunodeficiency disorders. This advanced genetic test specifically targets mutations in the CORO1A gene, which plays a critical role in immune system regulation and cellular function. CORO1A immunodeficiency type 8 is a rare autosomal recessive condition characterized by severe combined immunodeficiency (SCID) that affects multiple body systems including the immune system, skin, and skeletal development.
What Does This Test Measure and Detect?
Our state-of-the-art NGS genetic testing platform comprehensively analyzes the CORO1A gene to identify:
- Pathogenic variants and mutations in the CORO1A gene sequence
- Single nucleotide polymorphisms (SNPs) affecting protein function
- Insertions, deletions, and frameshift mutations
- Copy number variations impacting gene expression
- Regulatory region abnormalities affecting CORO1A protein production
The CORO1A gene encodes coronin-1A, a protein essential for T-cell survival, migration, and immune synapse formation. Mutations in this gene disrupt normal immune cell function, leading to the characteristic features of immunodeficiency type 8.
Who Should Consider CORO1A Genetic Testing?
This specialized genetic test is recommended for individuals presenting with:
- Recurrent severe infections starting in infancy or early childhood
- Unusual skin conditions including eczema, erythroderma, or skin infections
- Skeletal abnormalities such as short stature or bone deformities
- Autoimmune manifestations and inflammatory conditions
- Family history of primary immunodeficiency disorders
- Unexplained failure to thrive or developmental delays
- Abnormal immune cell counts on routine blood tests
Clinical Benefits of CORO1A Genetic Testing
Early and accurate diagnosis through CORO1A genetic testing provides numerous clinical advantages:
- Definitive Diagnosis: Confirms or rules out CORO1A-related immunodeficiency
- Personalized Treatment: Guides targeted therapeutic interventions
- Family Planning: Enables informed reproductive decisions and genetic counseling
- Proactive Management: Facilitates early intervention to prevent complications
- Comprehensive Care: Coordinates multidisciplinary approach involving immunologists, dermatologists, and genetic specialists
- Improved Outcomes: Reduces morbidity through timely and appropriate medical care
Understanding Your Test Results
Our comprehensive genetic report provides clear interpretation of your CORO1A gene analysis:
- Positive Result: Identifies pathogenic mutations confirming CORO1A immunodeficiency type 8 diagnosis
- Negative Result: No disease-causing variants detected in the CORO1A gene
- Variant of Uncertain Significance (VUS): Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Identifies individuals with one mutated copy who may pass the condition to offspring
All positive results include detailed clinical correlation and recommendations for follow-up care with appropriate specialists.
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | CORO1A Gene Immunodeficiency Type 8 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We provide comprehensive CORO1A genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing for patients nationwide.
Take Control of Your Genetic Health Today
Don’t let uncertainty about immune system disorders compromise your health and quality of life. Our CORO1A Gene Immunodeficiency Type 8 NGS Genetic DNA Test provides the definitive answers you need for proper diagnosis and management. With our discounted price of $500 USD and comprehensive genetic analysis, you can make informed decisions about your healthcare journey.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment or to speak with our genetic counseling team. Take the first step toward understanding your genetic health and securing personalized medical care.
