MMP20 Gene Amelogenesis Imperfecta Type 2A2 NGS Genetic DNA Test
Comprehensive Genetic Testing for Dental Enamel Disorders
The MMP20 Gene Amelogenesis Imperfecta Type 2A2 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for dental enamel disorders. This advanced test specifically targets the MMP20 gene, which plays a critical role in enamel matrix processing and mineralization. Amelogenesis Imperfecta type 2A2 is a hereditary condition characterized by defective enamel formation, leading to significant dental complications throughout life.
What Does This Test Measure and Detect?
This specialized genetic test utilizes cutting-edge Next-Generation Sequencing (NGS) technology to identify mutations in the MMP20 gene that are responsible for Amelogenesis Imperfecta type 2A2. The test specifically detects:
- Pathogenic variants in the MMP20 gene sequence
- Single nucleotide polymorphisms affecting enamel formation
- Insertion and deletion mutations disrupting protein function
- Genetic markers associated with autosomal recessive inheritance patterns
- Specific mutations that impair enamel matrix metalloproteinase-20 activity
Who Should Consider This Genetic Test?
This test is recommended for individuals experiencing symptoms or having risk factors for Amelogenesis Imperfecta type 2A2, including:
- Individuals with abnormal tooth coloration (yellow, brown, or gray teeth)
- Patients experiencing rapid tooth wear or enamel erosion
- Children with delayed or abnormal tooth eruption patterns
- Individuals with family history of enamel formation disorders
- Patients with increased tooth sensitivity to temperature changes
- Those with rough or pitted enamel surfaces
- Individuals requiring comprehensive dental treatment planning
Clinical Benefits of Genetic Testing
Undergoing the MMP20 Gene Amelogenesis Imperfecta Type 2A2 NGS Genetic DNA Test provides numerous clinical advantages:
- Accurate Diagnosis: Provides definitive genetic confirmation of Amelogenesis Imperfecta type 2A2
- Personalized Treatment Planning: Enables customized dental care strategies based on genetic findings
- Family Planning Guidance: Offers valuable information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates proactive dental management to prevent complications
- Comprehensive Risk Assessment: Identifies inheritance patterns for family members
- Psychological Relief: Provides clarity and understanding of the underlying condition
Understanding Your Test Results
Your genetic test results will be carefully analyzed and interpreted by our team of genetic specialists. The report will include:
- Positive Result: Indicates the presence of pathogenic MMP20 gene mutations associated with Amelogenesis Imperfecta type 2A2. This confirms the genetic basis of enamel formation disorders and guides appropriate dental management strategies.
- Negative Result: Suggests that no disease-causing mutations were detected in the MMP20 gene. However, other genetic or environmental factors may still contribute to enamel abnormalities.
- Variant of Uncertain Significance: Some genetic changes may have unknown clinical implications. These findings require careful interpretation and may necessitate additional family studies.
All results include detailed explanations and recommendations for follow-up care with dental and genetic specialists.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | MMP20 Gene Amelogenesis Imperfecta Type 2A2 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure you have:
- Complete clinical history of the patient
- Scheduled genetic counseling session to create a detailed family pedigree chart
- Documentation of family members affected with enamel formation disorders
- Previous dental records and imaging studies
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about enamel formation disorders affect your dental health and quality of life. The MMP20 Gene Amelogenesis Imperfecta Type 2A2 NGS Genetic DNA Test provides the genetic answers you need for informed dental care decisions.
Book your genetic test today by calling our dedicated patient care line at +1(267) 388-9828 or schedule your appointment online. Our genetic counselors are available to answer your questions and guide you through the testing process.
Take control of your dental health with advanced genetic diagnostics from General Genetics Corporation – your trusted partner in comprehensive genetic testing solutions.
