SIX1 Gene Deafness Autosomal Dominant Type 23 NGS Genetic DNA Test
Understanding SIX1 Gene-Related Hearing Loss
The SIX1 Gene Deafness Autosomal Dominant Type 23 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary hearing disorders. This specialized test focuses on identifying mutations in the SIX1 gene, which plays a critical role in the development and function of the inner ear structures essential for normal hearing. Autosomal dominant deafness type 23 is characterized by progressive hearing loss that typically begins in childhood or early adulthood and can significantly impact quality of life if left undiagnosed.
What Does This Test Measure?
Our advanced NGS-based genetic test specifically targets:
- Comprehensive analysis of the SIX1 gene sequence
- Detection of point mutations, insertions, and deletions
- Identification of pathogenic variants associated with autosomal dominant inheritance
- Assessment of genetic markers linked to progressive hearing impairment
- Evaluation of mutation impact on protein function and structure
Technical Excellence in Genetic Analysis
Utilizing state-of-the-art Next-Generation Sequencing technology, our test provides unparalleled accuracy in detecting even the most subtle genetic variations. The NGS platform enables simultaneous analysis of multiple genetic regions, ensuring comprehensive coverage of the SIX1 gene and its regulatory elements.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Progressive hearing loss beginning in childhood or early adulthood
- Family history of hereditary hearing impairment
- Unexplained sensorineural hearing loss
- Planning for family expansion with concerns about genetic inheritance
- Children with delayed speech development due to hearing issues
- Individuals with associated craniofacial abnormalities
Clinical Indications and Symptoms
Patients presenting with the following symptoms should consider genetic testing:
- Bilateral sensorineural hearing loss
- Progressive deterioration of hearing ability
- Difficulty understanding speech in noisy environments
- Family pattern of hearing loss across generations
- Associated vestibular dysfunction or balance issues
Benefits of SIX1 Genetic Testing
Undergoing genetic testing for SIX1-related deafness provides numerous advantages:
- Early Intervention Opportunities: Early detection enables timely implementation of hearing aids, cochlear implants, or other interventions
- Personalized Treatment Planning: Results guide ENT specialists in developing targeted treatment strategies
- Genetic Counseling Support: Comprehensive genetic counseling helps families understand inheritance patterns
- Reproductive Planning: Enables informed family planning decisions
- Proactive Management: Facilitates monitoring and management of progressive hearing loss
- Peace of Mind: Provides clarity and reduces uncertainty about genetic predisposition
Understanding Your Test Results
Our comprehensive genetic report includes:
- Positive Result: Indicates the presence of a pathogenic SIX1 gene mutation. This confirms the genetic basis of hearing loss and enables targeted management strategies.
- Negative Result: Suggests that SIX1 gene mutations are not responsible for the hearing loss, directing further investigation toward other genetic or environmental causes.
- Variant of Uncertain Significance (VUS): Some genetic changes may require additional family studies or research to determine clinical significance.
Post-Test Guidance
All positive results include detailed genetic counseling sessions to help patients and families understand the implications, inheritance patterns, and available management options. Our team works closely with ENT specialists to ensure coordinated care.
Test Pricing and Availability
| Test Name | Regular Price | Discount Price |
|---|---|---|
| SIX1 Gene Deafness Autosomal Dominant Type 23 NGS Genetic DNA Test | $700 USD | $500 USD |
Test Specifications
- Turnaround Time: 3 to 4 Weeks
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Technology: Next-Generation Sequencing (NGS)
- Specialty: ENT and Genetics
Nationwide Testing Availability
We have testing facilities and collection centers across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to genetic testing services regardless of your location.
Take Control of Your Genetic Health
Don’t let uncertainty about hereditary hearing loss impact your quality of life. Our SIX1 Gene Deafness Autosomal Dominant Type 23 NGS Genetic DNA Test provides the clarity and information needed to make informed healthcare decisions. With our discounted price of $500 USD and comprehensive genetic counseling support, you can take proactive steps toward better hearing health management.
Ready to schedule your genetic test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process.
