UGT1A1 Gene Polymorphism Nucleotide TA Repeats Detection Test
Understanding UGT1A1 Genetic Testing
The UGT1A1 Gene Polymorphism Nucleotide TA Repeats Detection Test represents a breakthrough in personalized medicine, offering crucial insights into how your body metabolizes specific medications. This advanced molecular diagnostic test examines the genetic variations in the UGT1A1 gene, which encodes the enzyme UDP-glucuronosyltransferase 1A1 responsible for processing numerous drugs and endogenous compounds.
What Does This Test Measure?
This sophisticated genetic analysis specifically detects the number of TA repeats in the promoter region of the UGT1A1 gene. The normal genotype contains six TA repeats (TA6), while variations with seven (TA7) or more repeats can significantly impact enzyme activity:
- TA6/TA6: Normal enzyme activity
- TA6/TA7: Reduced enzyme activity (heterozygous)
- TA7/TA7: Severely reduced enzyme activity (homozygous)
Who Should Consider This Test?
This genetic test is particularly important for individuals in specific clinical situations:
- Patients scheduled for chemotherapy with irinotecan or other UGT1A1-metabolized drugs
- Individuals with Gilbert’s syndrome or unexplained hyperbilirubinemia
- Patients experiencing adverse drug reactions to medications processed by UGT1A1
- Those requiring personalized dosing of UGT1A1 substrate medications
- Individuals with family history of drug metabolism issues
Clinical Benefits of UGT1A1 Testing
Understanding your UGT1A1 genetic profile offers numerous clinical advantages:
- Personalized Medication Dosing: Optimize drug dosages based on your genetic metabolism capacity
- Reduced Toxicity Risk: Minimize adverse effects from chemotherapy and other medications
- Improved Treatment Outcomes: Enhance therapeutic efficacy through genetic-guided prescribing
- Early Risk Identification: Identify genetic predisposition to drug metabolism issues before treatment begins
- Cost-Effective Healthcare: Reduce hospitalizations and complications from adverse drug reactions
Understanding Your Test Results
Your UGT1A1 genetic test results will provide valuable information about your drug metabolism capacity:
- Normal Metabolizer: Standard enzyme activity – typical medication dosing appropriate
- Intermediate Metabolizer: Reduced enzyme activity – may require dose adjustments
- Poor Metabolizer: Severely reduced enzyme activity – significant dose modifications or alternative medications recommended
Your healthcare provider will interpret these results in the context of your specific medical needs and treatment plans.
Test Information and Pricing
| Test Details | Information |
|---|---|
| Test Name | UGT1A1 Gene Polymorphism Nucleotide TA Repeats Detection Test |
| Regular Price | $300 USD |
| Discount Price | $188 USD |
| Turnaround Time | Sample: Mon/Wed by 9 am; Report: 7 Working Days |
| Sample Type | 4 mL (2 mL min.) whole Blood in 1 Lavender top (EDTA) tube |
| Methodology | PCR, Fragment Analysis |
| Specialties | Gastroenterologist, Oncologist |
Nationwide Testing Availability
GGC DNA provides comprehensive UGT1A1 genetic testing services across the United States. We have conveniently located branches in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more metropolitan areas. Our nationwide network ensures accessible, reliable genetic testing for patients throughout the country.
Take Control of Your Medication Safety
Don’t leave your medication response to chance. The UGT1A1 Gene Polymorphism Nucleotide TA Repeats Detection Test provides the genetic information needed to optimize your treatment and minimize risks. Our advanced molecular diagnostics laboratory utilizes state-of-the-art PCR and fragment analysis technology to deliver accurate, reliable results you can trust.
Ready to understand your genetic medication metabolism profile? Book your UGT1A1 genetic test today and take the first step toward personalized, safer medication management. Call us at +1(267) 388-9828 or schedule your appointment online.
Note: No special preparation required for this test. Ship samples refrigerated – DO NOT FREEZE.
