Quadruple Marker Test: Comprehensive Prenatal Screening
Understanding the Quadruple Marker Test
The Quadruple Marker Test represents a significant advancement in prenatal care, offering expectant parents valuable insights into their baby’s health and development. This sophisticated screening procedure analyzes four specific biochemical markers in maternal blood to assess the likelihood of certain chromosomal conditions and neural tube defects. As a non-invasive prenatal screening method, it provides crucial information without posing any risk to the developing fetus.
This test plays a vital role in modern obstetrics by helping healthcare providers identify pregnancies that may require additional diagnostic testing or specialized care. The Quadruple Marker Test is particularly valuable because it can detect potential issues early in pregnancy, allowing for timely interventions and informed decision-making.
What the Quadruple Marker Test Measures
The Quadruple Marker Test evaluates four essential substances in maternal blood:
- Alpha-fetoprotein (AFP): A protein produced by the fetal liver
- Human Chorionic Gonadotropin (hCG): A hormone produced by the placenta
- Unconjugated Estriol (uE3): An estrogen produced by both the fetus and placenta
- Inhibin A: A hormone produced by the placenta and ovaries
Using the advanced Chemiluminescent Immunoassay method, our laboratory precisely measures these markers to calculate risk probabilities for:
- Down syndrome (Trisomy 21)
- Edwards syndrome (Trisomy 18)
- Neural tube defects including spina bifida
- Abdominal wall defects
Who Should Consider the Quadruple Marker Test?
The Quadruple Marker Test is recommended for all pregnant women, particularly those who:
- Are between 15-20 weeks of gestation
- Are 35 years of age or older
- Have a family history of chromosomal abnormalities
- Have had previous pregnancies with birth defects
- Show abnormal ultrasound findings
- Have diabetes requiring insulin treatment
- Have been exposed to certain medications or environmental factors
Optimal Timing for Testing
The ideal window for the Quadruple Marker Test is between 15 and 20 weeks of pregnancy. This timing ensures optimal accuracy in detecting the biochemical markers while allowing sufficient time for follow-up testing if needed.
Benefits of Taking the Quadruple Marker Test
- Early Risk Assessment: Provides valuable information about potential chromosomal conditions
- Non-Invasive Procedure: Simple blood draw with no risk to the fetus
- Comprehensive Screening: Evaluates multiple conditions simultaneously
- Informed Decision Making: Helps parents and healthcare providers plan appropriate care
- Peace of Mind: Offers reassurance about fetal development
- Quick Results: Turnaround time of just 3-4 days
Understanding Your Test Results
Your Quadruple Marker Test results will be presented as risk ratios rather than definitive diagnoses. A “screen positive” result indicates an increased risk for certain conditions but does not confirm their presence. Conversely, a “screen negative” result suggests a lower probability but doesn’t guarantee the absence of abnormalities.
Interpreting Risk Levels
- Low Risk Results: Indicate reduced likelihood of the screened conditions
- High Risk Results: Suggest increased probability, requiring further diagnostic testing
- Borderline Results: May warrant repeat testing or additional monitoring
It’s essential to discuss your results with your healthcare provider, who can provide personalized interpretation and recommend appropriate next steps based on your individual circumstances.
Test Pricing and Information
| Test Component | Price (USD) |
|---|---|
| Discount Price | $112 |
| Regular Price | $150 |
| Sample Type | Serum (1-2ml) |
| Turnaround Time | 3-4 Days |
| Testing Method | Chemiluminescent Immunoassay |
Pre-Test Instructions
The Quadruple Marker Test typically requires a doctor’s prescription. However, prescription requirements may not apply for pregnancy-related screening, surgical preparation cases, or individuals planning international travel. Please consult with our healthcare professionals for specific requirements.
Nationwide Availability
GGC DNA has testing facilities conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible prenatal screening services for expectant parents throughout the country.
Take the Next Step in Your Prenatal Care
Don’t leave your pregnancy health to chance. The Quadruple Marker Test provides essential information that can significantly impact your prenatal care decisions. Our experienced healthcare team is ready to guide you through the testing process and help you understand your results.
Ready to schedule your Quadruple Marker Test? Contact us today at +1(267) 388-9828 to book your appointment or speak with our genetic counseling specialists. Take advantage of our special discounted price of $112 and ensure comprehensive prenatal screening for your peace of mind.
Early detection through advanced screening can make all the difference in your pregnancy journey. Trust GGC DNA for accurate, reliable prenatal testing services backed by cutting-edge technology and compassionate care.

