Nx Gen Sequencing Maturity Onset Diabetes of Young (MODY) Test
Understanding MODY Genetic Testing
Maturity Onset Diabetes of the Young (MODY) represents a unique form of diabetes characterized by autosomal dominant inheritance and early onset, typically before age 25. Unlike type 1 or type 2 diabetes, MODY results from single gene mutations that impair pancreatic beta-cell function. Our Nx Gen Sequencing MODY Test provides comprehensive genetic analysis to identify these specific mutations, enabling accurate diagnosis and personalized treatment approaches.
What This Test Measures and Detects
The Nx Gen Sequencing MODY Test utilizes cutting-edge Next Generation Sequencing technology to analyze 31 critical genes associated with monogenic diabetes:
- ABCC8, AKT2, APPL1, BLK, CEL, CISD2
- EIF2AK3, FOXP3, GCK, GLIS3, GLUD1, HADH
- HNF1A, HNF1B, HNF4A, IER3IP1, INS, INSR
- KCNJ11, KLF11, MNX1, NEUROD1, NKX2-2
- NKX6-1, PAX4, PDX1, PTF1A, RFX6, SLC2A2
- WFS1, ZFP57
This comprehensive panel detects mutations that affect insulin secretion, pancreatic development, and glucose metabolism regulation, providing crucial insights into the specific genetic cause of diabetes in young patients.
Who Should Consider MODY Genetic Testing
Clinical Indications and Symptoms
This test is particularly valuable for individuals presenting with:
- Diabetes diagnosis before age 25 with strong family history
- Atypical diabetes features not fitting type 1 or type 2 patterns
- Mild fasting hyperglycemia without typical diabetes symptoms
- Diabetes in multiple generations suggesting autosomal dominant inheritance
- Absence of pancreatic autoantibodies and insulin dependence
- Renal cysts or other extra-pancreatic features
- Response to specific oral medications rather than insulin
Benefits of MODY Genetic Testing
Undergoing genetic testing for MODY offers numerous advantages:
- Accurate Diagnosis: Differentiates MODY from other diabetes types
- Personalized Treatment: Enables targeted therapy based on genetic subtype
- Family Risk Assessment: Identifies at-risk relatives for early intervention
- Prognostic Information: Provides insights into disease progression
- Reproductive Counseling: Informs family planning decisions
- Cost-Effective Management: May reduce long-term treatment costs
- Psychological Benefits: Provides clarity and reduces diagnostic uncertainty
Understanding Your Test Results
Your MODY genetic test results will be carefully interpreted by our expert genetic counselors and endocrinologists:
- Positive Result: Identifies a pathogenic mutation confirming MODY diagnosis
- Negative Result: No mutation detected in tested genes
- Variant of Uncertain Significance: Genetic change with unclear clinical impact
- Carrier Status: Information about inherited risk factors
All results include comprehensive interpretation and recommendations for next steps. Our genetic counseling team provides detailed explanations and guidance for managing your condition based on the specific genetic findings.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | Nx Gen Sequencing Maturity Onset Diabetes of Young (MODY) Test |
| Discount Price | $500 USD |
| Regular Price | $764 USD |
| Turnaround Time | 30 Working Days |
| Sample Type | 4 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube |
| Shipping Instructions | Ship refrigerated. DO NOT FREEZE |
| Required Documentation | Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and many other cities. Our network ensures accessible genetic testing services nationwide.
Take Control of Your Diabetes Diagnosis Today
Don’t let diagnostic uncertainty delay proper treatment. Our MODY genetic testing provides the clarity needed for effective diabetes management. Early and accurate diagnosis can significantly impact treatment success and quality of life.
Ready to schedule your test? Contact us now:
Phone: +1(267) 388-9828
WhatsApp: +1(267) 388-9828
Our dedicated team is available to answer your questions, assist with scheduling, and provide guidance throughout the testing process. Take the first step toward personalized diabetes care today.
