CDK4 Gene Melanoma Cutaneous Malignant Familial CDK4 Related NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Melanoma Risk
The CDK4 Gene Melanoma Cutaneous Malignant Familial CDK4 Related NGS Genetic DNA Test represents a cutting-edge approach to identifying individuals at elevated risk for hereditary melanoma. This sophisticated diagnostic tool utilizes next-generation sequencing technology to detect mutations in the CDK4 gene, which plays a critical role in cell cycle regulation and melanoma development.
What Does This Test Measure?
This advanced genetic test specifically analyzes the CDK4 (Cyclin-Dependent Kinase 4) gene for pathogenic variants associated with familial cutaneous malignant melanoma. The test examines:
- CDK4 gene mutations linked to hereditary melanoma susceptibility
- Specific nucleotide changes affecting protein function
- Inherited genetic variations that increase melanoma risk
- Mutations that disrupt normal cell cycle control mechanisms
Who Should Consider CDK4 Genetic Testing?
This test is particularly recommended for individuals with:
- Personal history of multiple primary melanomas
- Family history of melanoma in first-degree relatives
- Early-onset melanoma diagnosis (before age 50)
- Family members with confirmed CDK4 mutations
- Multiple atypical moles or dysplastic nevi
- Personal or family history of pancreatic cancer
- Concerns about hereditary cancer risk patterns
Clinical Benefits of CDK4 Genetic Testing
Understanding your CDK4 genetic status provides numerous advantages:
- Personalized Risk Assessment: Determine your specific melanoma risk based on genetic factors
- Proactive Surveillance: Implement targeted screening protocols for early detection
- Family Planning: Make informed decisions about genetic risk to offspring
- Preventive Strategies: Develop sun protection and lifestyle modifications
- Treatment Guidance: Inform therapeutic decisions if melanoma develops
- Family Member Screening: Identify at-risk relatives for preventive care
Understanding Your Test Results
Your CDK4 genetic test results will fall into one of several categories:
- Positive Result: A pathogenic CDK4 mutation is detected, indicating increased melanoma risk and necessitating enhanced surveillance
- Negative Result: No known CDK4 mutations found, though other genetic factors may still contribute to melanoma risk
- Variant of Uncertain Significance: A genetic change is identified whose clinical significance requires further research
- No Mutation Detected: No CDK4 mutations identified in individuals with strong family history, suggesting other genetic factors may be involved
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | CDK4 Gene Melanoma Cutaneous Malignant Familial CDK4 Related NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) |
| Specialty | Oncology Genetics |
Pre-Test Requirements
Before undergoing CDK4 genetic testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session with certified genetic counselor
- Development of detailed family pedigree chart
- Discussion of potential implications and limitations
- Informed consent process
Nationwide Accessibility
We have conveniently located branches across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services for patients nationwide.
Take Control of Your Genetic Health
Understanding your CDK4 genetic status empowers you to make informed healthcare decisions and implement proactive melanoma prevention strategies. Our comprehensive genetic testing provides the clarity needed for personalized cancer risk management.
Ready to schedule your CDK4 genetic test? Contact us today at +1(267) 388-9828 or book your appointment online. Our genetic specialists are available to discuss your testing options and answer any questions about hereditary melanoma risk assessment.

