WRN Gene Werner Syndrome NGS Genetic DNA Test
Understanding Werner Syndrome and Genetic Testing
Werner Syndrome is a rare autosomal recessive disorder characterized by premature aging, typically manifesting in young adulthood. The WRN Gene Werner Syndrome NGS Genetic DNA Test represents a breakthrough in genetic diagnostics, offering precise detection of mutations in the WRN (WRN RecQ Like Helicase) gene responsible for this condition. This comprehensive analysis provides crucial insights for individuals and families affected by accelerated aging symptoms.
What Does the Test Measure?
This advanced genetic test specifically targets the WRN gene located on chromosome 8p12, utilizing Next Generation Sequencing (NGS) technology to identify pathogenic variants that cause Werner syndrome. The test detects:
- Point mutations in the WRN gene
- Small insertions and deletions
- Copy number variations
- Pathogenic variants affecting helicase function
Who Should Consider This Test?
Clinical Indications and Symptoms
This test is recommended for individuals presenting with:
- Premature aging symptoms appearing in adolescence or early adulthood
- Short stature and slender limbs with stocky trunk
- Early graying and thinning of hair
- Bilateral cataracts developing before age 40
- Skin changes including scleroderma-like features
- Family history of Werner syndrome or consanguinity
- Unexplained accelerated aging in young adults
- Multiple age-related conditions occurring prematurely
Benefits of WRN Gene Testing
Early genetic testing provides numerous advantages:
- Accurate Diagnosis: Confirms Werner syndrome with high precision
- Family Planning: Enables informed reproductive decisions
- Proactive Management: Facilitates early intervention and monitoring
- Genetic Counseling: Provides comprehensive family risk assessment
- Research Contribution: Advances understanding of aging mechanisms
Understanding Your Test Results
Interpretation Guidelines
Your genetic test results will fall into one of these categories:
- Positive Result: Identifies pathogenic variants in the WRN gene confirming Werner syndrome diagnosis
- Negative Result: No disease-causing variants detected, though clinical correlation is essential
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical evaluation
- Carrier Status: Identifies individuals carrying one copy of mutated WRN gene
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | WRN Gene Werner Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Methodology | Next Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Accessibility
General Genetics Corporation provides comprehensive genetic testing services across the United States. We have established branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to cutting-edge genetic diagnostics regardless of your location.
Take Control of Your Genetic Health
Early detection through genetic testing can significantly impact disease management and family planning decisions. The WRN Gene Werner Syndrome NGS Genetic DNA Test offers unparalleled accuracy in diagnosing this rare premature aging disorder. Our team of genetic specialists and counselors are dedicated to providing comprehensive support throughout your testing journey.
Book Your Test Today
Ready to take the next step in understanding your genetic health? Contact our genetic specialists to schedule your WRN Gene Werner Syndrome NGS Genetic DNA Test. Call or WhatsApp us at +1(267) 388-9828 to book your appointment and receive personalized genetic counseling. Early diagnosis leads to better management and improved quality of life for individuals affected by Werner syndrome.
