WNT3 Gene Tetraamelia Autosomal Recessive NGS Genetic DNA Test
Comprehensive Genetic Analysis for Limb Malformation Disorders
The WNT3 Gene Tetraamelia Autosomal Recessive NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare congenital disorders. This advanced testing methodology utilizes cutting-edge Next-Generation Sequencing (NGS) technology to identify mutations in the WNT3 gene, which plays a crucial role in embryonic development and limb formation. Understanding your genetic profile is essential for accurate diagnosis, informed family planning, and personalized medical management.
What Does This Test Measure?
This comprehensive genetic test specifically targets the WNT3 gene, analyzing it for mutations associated with tetraamelia syndrome. The test examines:
- Complete sequencing of the WNT3 gene coding regions
- Detection of point mutations, insertions, and deletions
- Identification of autosomal recessive inheritance patterns
- Analysis of genetic variants affecting limb development
- Assessment of mutation impact on protein function
Who Should Consider This Test?
This genetic test is recommended for individuals and families experiencing specific clinical scenarios:
- Families with history of tetraamelia or severe limb malformations
- Couples planning pregnancy with known family history of WNT3 mutations
- Individuals with congenital limb abnormalities seeking genetic diagnosis
- Parents of children born with complete absence of limbs
- Individuals with family members diagnosed with tetraamelia syndrome
- Couples seeking preconception genetic screening for rare disorders
Clinical Symptoms and Indications
Tetraamelia syndrome presents with distinct clinical features that warrant genetic testing:
- Complete absence of all four limbs (arms and legs)
- Facial dysmorphism and craniofacial abnormalities
- Urogenital malformations and renal abnormalities
- Cardiac defects and pulmonary hypoplasia
- Vertebral anomalies and spinal malformations
- Developmental delays in some cases
Benefits of WNT3 Genetic Testing
Accurate Diagnosis and Prognosis
Our advanced NGS technology provides unparalleled accuracy in detecting WNT3 gene mutations, enabling:
- Definitive diagnosis of tetraamelia syndrome
- Clear understanding of inheritance patterns
- Accurate recurrence risk assessment for future pregnancies
- Personalized medical management strategies
- Early intervention planning for affected individuals
Family Planning Advantages
Genetic testing provides crucial information for reproductive decisions:
- Informed family planning choices
- Preimplantation genetic diagnosis options
- Prenatal testing availability for at-risk pregnancies
- Genetic counseling guidance for inheritance patterns
- Reduced uncertainty in reproductive decisions
Understanding Your Test Results
Positive Result Interpretation
A positive result indicates the presence of WNT3 gene mutations:
- Confirms diagnosis of tetraamelia syndrome
- Identifies specific mutation for targeted management
- Provides recurrence risk information (25% for autosomal recessive)
- Enables carrier testing for family members
- Facilitates genetic counseling sessions
Negative Result Interpretation
A negative result provides valuable clinical information:
- Rules out WNT3-related tetraamelia in most cases
- Suggests alternative genetic causes for limb abnormalities
- Provides reassurance for family planning
- May indicate need for additional genetic testing
- Helps narrow differential diagnosis
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | WNT3 Gene Tetraamelia Autosomal Recessive NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Specialty | Pediatrics |
| Department | Genetics |
| Method | NGS Technology |
| Disease Type | Dysmorphology |
Pre-Test Requirements
To ensure accurate testing and comprehensive results, we require:
- Complete clinical history of the patient undergoing testing
- Genetic counseling session prior to testing
- Detailed pedigree chart of family members affected with WNT3 gene mutations
- Informed consent for genetic testing
- Appropriate sample collection following specific guidelines
Nationwide Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and medical professionals ensures you receive comprehensive care regardless of your location.
Take Control of Your Genetic Health
Don’t let uncertainty about genetic conditions affect your family’s future. Our WNT3 Gene Tetraamelia Autosomal Recessive NGS Genetic DNA Test provides the clarity and confidence you need for informed medical decisions and family planning. With our discounted price of $500 USD and comprehensive genetic analysis, you’re investing in accurate diagnosis and peace of mind.
Ready to schedule your genetic test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
Take the first step toward understanding your genetic health and making informed decisions for your family’s future. Book your WNT3 genetic test today!
