UMOD Gene Glomerulocystic Kidney Disease with Hyperuricemia and Isosthenuria NGS Genetic DNA Test
Comprehensive Genetic Testing for Kidney Disorders
The UMOD Gene Glomerulocystic Kidney Disease with Hyperuricemia and Isosthenuria NGS Genetic DNA Test represents a breakthrough in precision medicine for diagnosing rare inherited kidney conditions. This advanced genetic test specifically targets mutations in the UMOD gene, which encodes uromodulin – the most abundant protein in normal urine. Uromodulin plays crucial roles in kidney function, including protection against urinary tract infections, regulation of salt balance, and prevention of kidney stone formation.
What This Revolutionary Test Detects
Our state-of-the-art Next-Generation Sequencing (NGS) technology comprehensively analyzes the UMOD gene to identify pathogenic variants associated with:
- Glomerulocystic kidney disease – abnormal cyst development in kidney glomeruli
- Hyperuricemia – elevated blood uric acid levels leading to gout and kidney stones
- Isosthenuria – impaired urine concentration ability
- Autosomal dominant tubulointerstitial kidney disease (ADTKD)
- Familial juvenile hyperuricemic nephropathy (FJHN)
Who Should Consider This Genetic Test?
Clinical Indications and Symptoms
This test is recommended for individuals experiencing:
- Unexplained chronic kidney disease with progressive decline in function
- Early-onset gout or recurrent kidney stones
- Family history of kidney disease across multiple generations
- Difficulty concentrating urine despite adequate hydration
- Elevated serum uric acid levels without clear cause
- Abnormal kidney imaging showing cystic changes
- Hypertension developing at young age
- Proteinuria or hematuria of unknown origin
Significant Benefits of UMOD Genetic Testing
Transformative Diagnostic Advantages
- Precise Diagnosis: Eliminates diagnostic uncertainty and provides definitive answers
- Early Intervention: Enables proactive management before significant kidney damage occurs
- Personalized Treatment: Guides targeted therapies for hyperuricemia and kidney protection
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Prognostic Information: Helps predict disease progression and outcomes
- Cost-Effective Care: Reduces unnecessary testing and inappropriate treatments
Understanding Your Test Results
Comprehensive Genetic Analysis Interpretation
Our expert genetic counselors provide detailed interpretation of your results:
Positive Result
A positive result indicates the presence of a pathogenic UMOD gene mutation. This confirms the genetic basis of your kidney condition and enables:
- Implementation of uric acid-lowering therapies
- Regular kidney function monitoring
- Blood pressure management strategies
- Dietary modifications to protect kidney health
- Family member screening recommendations
Negative Result
A negative result suggests that UMOD mutations are not the cause of your symptoms, directing further evaluation toward other potential causes of kidney disease.
Variant of Uncertain Significance (VUS)
Some genetic changes require additional research. Our team provides ongoing monitoring and reclassification as new evidence emerges.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Convenient Nationwide Access
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Comprehensive Testing Process
Sample Collection and Analysis
Our testing process is designed for maximum convenience and accuracy:
- Sample Types: Blood, Extracted DNA, or One drop of Blood on FTA Card
- Turnaround Time: 3 to 4 weeks for comprehensive results
- Pre-test Requirements: Complete clinical history and genetic counseling session
- Technology: Advanced Next-Generation Sequencing (NGS) methodology
Essential Pre-test Preparation
To ensure optimal testing outcomes, we require:
- Detailed clinical history of the patient
- Genetic counseling session to create a comprehensive family pedigree
- Documentation of affected family members with similar symptoms
- Review of previous kidney function tests and imaging studies
Take Control of Your Kidney Health Today
Don’t let uncertainty about your kidney health continue. Our UMOD Gene Glomerulocystic Kidney Disease with Hyperuricemia and Isosthenuria NGS Genetic DNA Test provides the clarity you need for informed medical decisions. With our discounted price of $500 USD and comprehensive genetic counseling support, you can access world-class diagnostic expertise.
Call our genetic specialists now at +1(267) 388-9828 to schedule your test and genetic counseling session. Our team is ready to help you understand your genetic risks and develop a personalized management plan for optimal kidney health.
Early genetic diagnosis can significantly impact disease progression and quality of life. Take the first step toward definitive answers and targeted treatment by booking your UMOD genetic test today.
