SUFU Gene Medulloblastoma Desmoplastic Familial NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Brain Cancer Risk
The SUFU Gene Medulloblastoma Desmoplastic Familial NGS Genetic DNA Test represents a breakthrough in precision medicine for cancer risk assessment. This advanced genetic screening specifically targets mutations in the SUFU (Suppressor of Fused) gene, which plays a critical role in the Hedgehog signaling pathway. When this pathway becomes dysregulated due to SUFU mutations, it significantly increases susceptibility to medulloblastoma, particularly the desmoplastic variant that often presents in childhood.
What This Test Measures and Detects
Our comprehensive NGS-based analysis examines the entire SUFU gene sequence to identify:
- Pathogenic variants and mutations in the SUFU gene
- Single nucleotide polymorphisms (SNPs) associated with increased cancer risk
- Copy number variations that may impact gene function
- Inherited genetic markers for familial cancer syndromes
- Specific mutations linked to Gorlin syndrome (nevoid basal cell carcinoma syndrome)
Who Should Consider This Genetic Test
This specialized genetic screening is particularly recommended for individuals with:
- Personal history of medulloblastoma, especially desmoplastic/nodular subtype
- Family history of childhood brain tumors or medulloblastoma
- Diagnosis of Gorlin syndrome or related conditions
- Multiple basal cell carcinomas at young age
- Family members with known SUFU gene mutations
- Unexplained developmental abnormalities or skeletal issues
- Planning pregnancy with family cancer history
Significant Benefits of SUFU Genetic Testing
Undergoing this comprehensive genetic assessment provides numerous advantages:
- Early Risk Identification: Detect genetic predisposition before cancer development
- Personalized Screening: Implement targeted surveillance protocols
- Family Planning Guidance: Make informed reproductive decisions
- Proactive Management: Develop preventive healthcare strategies
- Peace of Mind: Reduce uncertainty about hereditary cancer risk
- Clinical Trial Eligibility: Access to specialized prevention studies
Understanding Your Test Results
Our genetic counselors provide comprehensive result interpretation:
- Positive Result: Indicates presence of SUFU gene mutation requiring specialized medical follow-up and family screening
- Negative Result: No detected mutation, though continued routine screening may be recommended based on family history
- Variant of Uncertain Significance: Requires additional family studies and ongoing research correlation
- Professional Genetic Counseling: Included with all results to ensure complete understanding and next steps
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | SUFU Gene Medulloblastoma Desmoplastic Familial NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before testing, we require:
- Complete clinical history of the patient
- Genetic counseling session with our certified genetic counselors
- Detailed pedigree chart documenting family members affected by SUFU-related conditions
- Informed consent understanding test implications and potential outcomes
Nationwide Accessibility
GGC DNA maintains testing facilities across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services for patients nationwide.
Take Control of Your Genetic Health Today
Don’t let uncertainty about hereditary cancer risk impact your family’s future. Our SUFU Gene Medulloblastoma Desmoplastic Familial NGS Genetic DNA Test provides the clarity and actionable information needed for proactive health management. With advanced NGS technology and expert genetic counseling, you can make informed decisions about your healthcare journey.
Ready to schedule your genetic test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic cancer risk and protecting your family’s health for generations to come.
