STK11 Gene Peutz-Jeghers Syndrome NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Cancer Risk
The STK11 Gene Peutz-Jeghers Syndrome NGS Genetic DNA Test represents a breakthrough in personalized cancer risk assessment. This advanced diagnostic tool utilizes next-generation sequencing technology to analyze the STK11 gene, which plays a critical role in tumor suppression and cellular regulation. When mutations occur in this gene, individuals face significantly elevated risks for developing Peutz-Jeghers syndrome—a rare autosomal dominant condition characterized by gastrointestinal polyps, distinctive mucocutaneous pigmentation, and increased cancer susceptibility.
What This Test Measures and Detects
Our comprehensive NGS analysis examines the entire coding region of the STK11 gene to identify:
- Pathogenic variants and mutations in the STK11 gene
- Single nucleotide polymorphisms (SNPs) associated with cancer risk
- Insertions, deletions, and frameshift mutations
- Splice site variants affecting gene function
- Copy number variations impacting gene dosage
The test provides definitive information about genetic predisposition to multiple cancer types, including gastrointestinal cancers, breast cancer, pancreatic cancer, and gynecological malignancies. By identifying specific STK11 mutations, healthcare providers can implement targeted surveillance and preventive strategies.
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Characteristic dark blue or brown freckle-like spots on lips, mouth, eyes, or fingers
- Multiple gastrointestinal polyps detected during colonoscopy
- Family history of Peutz-Jeghers syndrome or related cancers
- Unexplained abdominal pain, rectal bleeding, or bowel obstruction
- Personal history of multiple cancer types at young age
- Relatives with confirmed STK11 gene mutations
- Children with pigmented oral lesions and gastrointestinal symptoms
Significant Benefits of Genetic Testing
Undergoing STK11 genetic testing provides numerous advantages:
- Early Risk Identification: Detect cancer predisposition before symptoms develop
- Personalized Screening: Implement targeted cancer surveillance protocols
- Family Planning Guidance: Make informed reproductive decisions
- Proactive Management: Develop preventive healthcare strategies
- Peace of Mind: Reduce uncertainty about hereditary cancer risks
- Comprehensive Care: Access specialized monitoring and treatment options
Understanding Your Test Results
Our genetic counselors provide detailed interpretation of your results:
- Positive Result: Indicates presence of STK11 mutation, confirming Peutz-Jeghers syndrome diagnosis and increased cancer risk. Requires specialized surveillance and management.
- Negative Result: No pathogenic STK11 mutations detected, though family history may still warrant monitoring.
- Variant of Uncertain Significance: Genetic change identified with unknown clinical impact, requiring ongoing research and family studies.
- Family Implications: Results may have significance for blood relatives, who should consider genetic counseling.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| STK11 Gene Peutz-Jeghers Syndrome NGS Genetic DNA Test | $700 |
| Discount Price | $500 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Pre-test Requirements: Clinical History and Genetic Counseling Session
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Control of Your Genetic Health Today
Don’t wait to understand your hereditary cancer risks. Our team of board-certified genetic counselors and oncology specialists are ready to guide you through the testing process and help you develop a personalized healthcare plan based on your genetic profile.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your STK11 Gene Peutz-Jeghers Syndrome NGS Genetic DNA Test. Take the first step toward proactive cancer prevention and personalized healthcare management.
