Solid Tumor Combo2 MSI NRAS KRAS BRAF HRAS Genetic Test
Comprehensive Genetic Analysis for Solid Tumor Management
The Solid Tumor Combo2 MSI NRAS KRAS BRAF HRAS Genetic Test represents a cutting-edge molecular diagnostic approach for comprehensive cancer profiling. This advanced panel simultaneously analyzes five critical genetic biomarkers that play pivotal roles in cancer development, progression, and treatment response. By examining these key molecular targets, healthcare providers can make more informed decisions about targeted therapies and immunotherapies, ultimately improving patient outcomes through precision medicine.
What This Test Measures and Detects
This comprehensive genetic panel evaluates multiple critical biomarkers:
- Microsatellite Instability (MSI): Detects DNA mismatch repair deficiencies that indicate potential responsiveness to immunotherapy
- NRAS Mutations: Identifies alterations in the NRAS oncogene associated with various solid tumors
- KRAS Mutations: Screens for KRAS gene variations that influence treatment selection
- BRAF Mutations: Detects BRAF V600E and other mutations critical for targeted therapy decisions
- HRAS Mutations: Identifies HRAS gene alterations in multiple cancer types
Who Should Consider This Test
This comprehensive genetic panel is particularly beneficial for patients with:
- Newly diagnosed solid tumors requiring treatment planning
- Advanced or metastatic cancers where targeted therapy options are being considered
- Colorectal, lung, melanoma, or other solid tumors where MSI status impacts treatment
- Cancers that have progressed on standard therapies
- Patients being evaluated for immunotherapy eligibility
- Individuals with family history of cancer syndromes
Key Benefits of Genetic Testing
- Personalized Treatment Selection: Identifies specific genetic alterations that respond to targeted therapies
- Immunotherapy Guidance: MSI status helps determine eligibility for immune checkpoint inhibitors
- Prognostic Information: Provides insights into disease progression and potential outcomes
- Clinical Trial Eligibility: May identify patients suitable for specific clinical trials
- Comprehensive Analysis: Multiple biomarkers analyzed simultaneously for efficiency
- Treatment Optimization: Helps avoid ineffective treatments and associated side effects
Understanding Your Test Results
Your test results will provide detailed information about the genetic status of your tumor:
- MSI Status: Results indicate microsatellite stable (MSS) or unstable (MSI-H) status
- Mutation Profiles: Specific genetic alterations detected in NRAS, KRAS, BRAF, and HRAS genes
- Clinical Implications: How detected mutations may impact treatment options
- Therapeutic Recommendations: Potential targeted therapy options based on genetic findings
Your healthcare provider will discuss the results in detail and explain how they relate to your specific cancer type and treatment plan. Positive findings for specific mutations may open up targeted therapy options, while MSI-H status may indicate potential benefit from immunotherapy.
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| Solid Tumor Combo2 MSI NRAS KRAS BRAF HRAS Genetic Test | $900 (Discounted from $1200) |
Test Specifications
- Turnaround Time: 10 days
- Sample Requirements: Tumor tissue (paraffin embedded blocks) and peripheral blood (EDTA Vacutainer 2ml)
- Testing Methodology: Sanger Sequencing and Fragment Analysis
- Prescription Requirements: Doctor’s prescription required (not applicable for surgery, pregnancy, or travel abroad cases)
Nationwide Testing Availability
We have testing facilities conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services for patients nationwide.
Take the Next Step in Your Cancer Care
Understanding your tumor’s genetic profile is crucial for making informed treatment decisions. Our Solid Tumor Combo2 MSI NRAS KRAS BRAF HRAS Genetic Test provides comprehensive insights that can guide your oncology team in developing the most effective treatment strategy.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our genetic counseling team is available to answer your questions and help you understand how this testing can benefit your specific situation.
