SCN5A Gene Brugada Syndrome Type 1 NGS Genetic DNA Test
Understanding SCN5A Gene Brugada Syndrome Type 1
The SCN5A Gene Brugada Syndrome Type 1 NGS Genetic DNA Test represents a breakthrough in cardiac genetic diagnostics, offering comprehensive analysis of the SCN5A gene mutations responsible for Brugada Syndrome Type 1. This inherited cardiac condition affects the heart’s electrical system, potentially leading to dangerous arrhythmias and sudden cardiac death. Our advanced testing methodology provides crucial insights for individuals and families affected by this serious genetic disorder.
What This Test Measures and Detects
This specialized genetic test utilizes Next-Generation Sequencing (NGS) technology to thoroughly examine the SCN5A gene, which encodes the cardiac sodium channel Nav1.5. The test specifically identifies:
- Pathogenic variants in the SCN5A gene associated with Brugada Syndrome Type 1
- Missense mutations, nonsense mutations, and frameshift variants
- Genetic alterations affecting sodium channel function
- Inheritance patterns within families
- Risk stratification for cardiac events
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing specific symptoms or having concerning family history:
- Patients with unexplained syncope or fainting episodes
- Individuals with family history of sudden cardiac death
- Those with characteristic ECG patterns suggestive of Brugada Syndrome
- Family members of diagnosed Brugada Syndrome patients
- Individuals with nocturnal agonal respiration or seizure-like episodes
- Patients with unexplained ventricular arrhythmias
Clinical Indications and Symptoms
Common clinical presentations that warrant SCN5A genetic testing include:
- ST-segment elevation in right precordial leads on ECG
- Fever-induced arrhythmic events
- Family history of sudden unexplained death syndrome (SUDS)
- Drug-induced Brugada pattern on ECG
- Unexplained cardiac arrest in young individuals
Benefits of SCN5A Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages for patients and their families:
- Early Risk Identification: Detect genetic predisposition before symptom onset
- Family Screening: Enable proactive testing of at-risk relatives
- Personalized Treatment: Guide appropriate medical management strategies
- Lifestyle Guidance: Provide specific recommendations to minimize risk
- Reproductive Planning: Inform family planning decisions
- Peace of Mind: Reduce uncertainty through definitive diagnosis
Medical Management Implications
Positive test results can significantly impact clinical care by:
- Guiding decisions about implantable cardioverter-defibrillator (ICD) placement
- Informing medication choices and avoiding pro-arrhythmic drugs
- Establishing appropriate follow-up and monitoring protocols
- Developing emergency action plans for affected individuals
Understanding Your Test Results
Our comprehensive genetic counseling services help you interpret your SCN5A test results:
Possible Result Interpretations
- Positive Result: Indicates presence of a pathogenic SCN5A mutation associated with increased risk of cardiac events
- Negative Result: No disease-causing mutation detected, though clinical follow-up may still be recommended
- Variant of Uncertain Significance (VUS): Requires additional family studies and clinical correlation
- Benign Variant: Genetic change not associated with increased disease risk
Post-Test Recommendations
Based on your results, our genetic specialists provide:
- Detailed explanation of genetic findings and their implications
- Referral to cardiac electrophysiology specialists when indicated
- Family testing recommendations and coordination
- Long-term management and surveillance plans
- Lifestyle modification guidance specific to your genetic profile
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | SCN5A Gene Brugada Syndrome Type 1 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Cardiology and Genetics |
Pre-Test Requirements
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Review of existing cardiac testing and ECG results
- Discussion of testing implications and potential outcomes
Nationwide Testing Availability
We proudly offer the SCN5A Gene Brugada Syndrome Type 1 NGS Genetic DNA Test across our extensive network of testing facilities throughout the United States. Our state-of-the-art laboratories and experienced genetic counselors serve patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more locations nationwide.
Why Choose Our Genetic Testing Services
- Board-certified genetic counselors and cardiologists
- CLIA-certified laboratory facilities
- Comprehensive pre- and post-test genetic counseling
- Rapid turnaround with accurate results
- Insurance coordination and billing support
- Ongoing patient support and follow-up care
Take Control of Your Cardiac Health Today
Don’t wait to address potential genetic cardiac risks. Our SCN5A Gene Brugada Syndrome Type 1 NGS Genetic DNA Test provides the critical information needed to protect your heart health and potentially save lives. With our discounted price of $500 USD, comprehensive genetic analysis is more accessible than ever.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and testing appointment. Our dedicated team is ready to guide you through every step of the process and provide the expert care you deserve.
Early detection through genetic testing can make the difference between life and death for individuals at risk of Brugada Syndrome. Take the first step toward proactive cardiac health management by booking your test today.
