SATB2 Gene Glass Syndrome NGS Genetic DNA Test
Comprehensive Genetic Analysis for Developmental Disorders
The SATB2 Gene Glass Syndrome NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for neurodevelopmental conditions. This advanced testing method utilizes Next-Generation Sequencing (NGS) technology to provide comprehensive analysis of the SATB2 gene, which plays a critical role in brain development and craniofacial formation. Glass syndrome, also known as SATB2-associated syndrome, is a rare genetic disorder characterized by significant developmental challenges that require precise diagnosis for optimal management and care planning.
What Does the SATB2 Gene Glass Syndrome Test Measure?
This sophisticated genetic test specifically targets and analyzes the SATB2 (Special AT-rich sequence-binding protein 2) gene, which functions as a crucial transcriptional regulator in neural development. The test detects:
- Point mutations and single nucleotide variants in the SATB2 gene
- Small insertions and deletions affecting gene function
- Copy number variations and structural abnormalities
- Pathogenic variants associated with Glass syndrome
- Both inherited and de novo (new) mutations
The NGS technology employed provides high-resolution analysis of the entire coding region and critical regulatory elements of the SATB2 gene, ensuring comprehensive coverage and accurate detection of genetic variations responsible for the clinical manifestations of Glass syndrome.
Who Should Consider SATB2 Genetic Testing?
This test is particularly recommended for individuals presenting with the following clinical features:
- Developmental Delays: Significant delays in reaching developmental milestones
- Intellectual Disability: Ranging from mild to severe cognitive impairment
- Speech and Language Disorders: Severe speech delay or absence of speech
- Craniofacial Abnormalities: Distinctive facial features including prominent forehead, down-slanting palpebral fissures, and dental anomalies
- Behavioral Characteristics: Autism spectrum features, anxiety, or attention deficits
- Feeding Difficulties: Oral motor dysfunction and feeding challenges in infancy
- Growth Issues: Short stature or failure to thrive
- Family History: Individuals with family members diagnosed with Glass syndrome or similar neurodevelopmental conditions
Key Benefits of SATB2 Genetic Testing
Undergoing SATB2 genetic testing provides numerous advantages for patients and families:
- Accurate Diagnosis: Provides definitive diagnosis, eliminating diagnostic uncertainty
- Personalized Care Planning: Enables development of targeted intervention strategies
- Early Intervention: Facilitates early implementation of appropriate therapies and support services
- Genetic Counseling: Provides basis for informed reproductive decision-making
- Family Risk Assessment: Identifies recurrence risks for family members
- Research Participation: Opens opportunities for involvement in clinical trials and research studies
- Educational Planning: Informs development of appropriate educational accommodations
- Medical Management: Guides monitoring for associated health concerns
Understanding Your Test Results
Interpreting SATB2 genetic test results requires professional genetic counseling. Results typically fall into several categories:
- Positive Result: Identification of a pathogenic variant in the SATB2 gene confirms the diagnosis of Glass syndrome and provides information about inheritance pattern
- Negative Result: No pathogenic variants detected, though this does not completely rule out the condition if clinical features strongly suggest Glass syndrome
- Variant of Uncertain Significance (VUS): Identification of genetic changes with unknown clinical significance requiring further evaluation
- Carrier Status: Identification of individuals who carry one copy of a mutated gene but may not show symptoms
Our genetic counselors provide comprehensive result interpretation and guidance on next steps, including recommendations for medical management, therapeutic interventions, and family planning considerations.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | SATB2 Gene Glass Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Specialty | Pediatrics |
| Department | Genetics |
| Method | NGS Technology |
| Disease Type | Dysmorphology |
Pre-Test Requirements
Before undergoing SATB2 genetic testing, patients should complete the following:
- Provide comprehensive clinical history including developmental milestones and current symptoms
- Participate in a genetic counseling session to discuss testing implications and expectations
- Complete a detailed pedigree chart documenting family history of similar conditions
- Understand the potential outcomes and implications of test results
- Provide informed consent for genetic testing
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified genetic counselors and medical professionals ensures consistent, high-quality care regardless of location.
Take the Next Step Toward Clarity
If you or your loved one is experiencing symptoms suggestive of Glass syndrome, don’t delay in seeking answers. Our SATB2 genetic testing provides the clarity needed to make informed decisions about care and management. With our discounted price of $500 USD and comprehensive genetic counseling support, you can access world-class diagnostic services without financial burden.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your SATB2 Gene Glass Syndrome NGS Genetic DNA Test. Our compassionate team is ready to guide you through every step of the testing process and help you understand your results.
