RUNX1 Gene Leukemia Acute Myeloid NGS Genetic DNA Test
Comprehensive Genetic Assessment for Leukemia Risk
The RUNX1 Gene Leukemia Acute Myeloid NGS Genetic DNA Test represents a breakthrough in personalized cancer risk assessment. This advanced diagnostic tool specifically examines the RUNX1 (Runt-related transcription factor 1) gene, which serves as a master regulator of hematopoiesis – the process of blood cell formation. Mutations in this critical gene have been directly linked to familial platelet disorder with predisposition to acute myeloid leukemia (FPD/AML), making this test essential for individuals with family histories of blood disorders.
What Does This Test Measure?
Our sophisticated NGS (Next-Generation Sequencing) technology comprehensively analyzes the entire RUNX1 gene to identify:
- Point mutations affecting single DNA nucleotides
- Insertions and deletions that disrupt gene function
- Frameshift mutations altering protein structure
- Missense and nonsense mutations impacting gene expression
- Regulatory region variations affecting gene activity
Who Should Consider This Test?
This genetic screening is particularly recommended for individuals experiencing:
- Unexplained bruising or bleeding tendencies
- Persistent fatigue and unexplained anemia
- Recurrent infections suggesting immune dysfunction
- Family history of acute myeloid leukemia or other blood cancers
- Known RUNX1 mutations in close relatives
- Unexplained low platelet counts (thrombocytopenia)
- Multiple family members with blood disorders
Key Benefits of RUNX1 Genetic Testing
- Early Risk Identification: Detect genetic predisposition before symptoms develop
- Personalized Monitoring: Implement targeted surveillance strategies
- Family Planning Guidance: Understand inheritance patterns for future generations
- Treatment Optimization: Inform potential therapeutic approaches if needed
- Peace of Mind: Clarify genetic status and reduce uncertainty
Understanding Your Test Results
Our comprehensive genetic counseling team will help interpret your results:
- Negative Result: No RUNX1 mutations detected – standard cancer screening recommended
- Positive Result: RUNX1 mutation identified – personalized monitoring plan developed
- Variant of Uncertain Significance: Additional family testing may be recommended
- Carrier Status: Information about inheritance patterns and family implications
Test Pricing Information
| Test Description | Price (USD) |
|---|---|
| RUNX1 Gene Leukemia Acute Myeloid NGS Genetic DNA Test – Discount Price | $500 |
| RUNX1 Gene Leukemia Acute Myeloid NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and oncology specialists ensures you receive comprehensive care regardless of your location.
Take Control of Your Genetic Health Today
Don’t wait to understand your genetic cancer risk. Our RUNX1 gene testing provides crucial information that could save lives through early detection and proactive management. Schedule your genetic counseling session and testing appointment by calling our dedicated genetics hotline at +1(267) 388-9828 or book online through our secure patient portal.
Important Note: All patients undergo pre-test genetic counseling and provide clinical history. Testing requires either blood sample, extracted DNA, or one drop of blood on FTA card. Results are typically available within 3-4 weeks from sample receipt.
