Protein S Antigen Free Test
Understanding Protein S Antigen Free Testing
The Protein S Antigen Free Test represents a critical advancement in coagulation diagnostics, specifically designed to evaluate the functional activity of Protein S in your bloodstream. Protein S serves as an essential natural anticoagulant that works in conjunction with activated Protein C to regulate the clotting cascade and prevent excessive thrombus formation. This sophisticated laboratory analysis measures the unbound, biologically active form of Protein S that circulates freely in plasma, providing clinicians with precise information about your body’s natural anticoagulation capacity.
What Does the Protein S Antigen Free Test Measure?
This specialized diagnostic assessment specifically quantifies the concentration of free Protein S antigen in your blood plasma. Unlike total Protein S measurements, this test focuses exclusively on the unbound fraction that remains biologically active and capable of participating in the anticoagulation process. The test evaluates:
- Free circulating Protein S antigen levels
- Functional anticoagulation capacity
- Risk assessment for thrombophilia
- Inherited or acquired Protein S deficiencies
Who Should Consider Protein S Antigen Free Testing?
This comprehensive diagnostic evaluation is particularly recommended for individuals experiencing specific clinical scenarios or exhibiting concerning symptoms that may indicate coagulation abnormalities:
Clinical Indications and Symptoms
- Personal history of unexplained venous thromboembolism
- Recurrent deep vein thrombosis (DVT) episodes
- Pulmonary embolism without clear risk factors
- Family history of thrombophilia or clotting disorders
- Women experiencing recurrent pregnancy loss
- Unexplained arterial thrombosis in young patients
- Suspected inherited coagulation deficiencies
- Monitoring anticoagulation therapy effectiveness
Comprehensive Benefits of Protein S Testing
Undergoing Protein S Antigen Free testing provides numerous clinical advantages for both patients and healthcare providers:
Diagnostic and Clinical Advantages
- Accurate Thrombophilia Assessment: Precisely identifies Protein S deficiency as a contributing factor to clotting disorders
- Personalized Treatment Planning: Enables healthcare providers to develop targeted anticoagulation strategies
- Family Risk Evaluation: Helps identify inherited coagulation disorders affecting multiple family members
- Pregnancy Management: Assists in managing thrombophilia risks during pregnancy and postpartum periods
- Preventive Care Guidance: Informs decisions about prophylactic anticoagulation in high-risk situations
- Treatment Monitoring: Tracks the effectiveness of anticoagulation therapy over time
Understanding Your Test Results
Interpreting Protein S Antigen Free test results requires careful consideration of multiple clinical factors. Our expert hematologists provide comprehensive guidance:
Result Interpretation Guidelines
- Normal Range: Typically 60-130% of normal pool, indicating adequate natural anticoagulation capacity
- Mild Deficiency: 40-59% may suggest increased thrombosis risk requiring monitoring
- Moderate Deficiency: 20-39% often indicates significant thrombophilia risk
- Severe Deficiency: Below 20% suggests high-risk condition requiring immediate intervention
- Contextual Interpretation: Results must be evaluated considering clinical history, medications, and concurrent conditions
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $176 |
| Regular Price | $300 |
Service Details
- Turnaround Time: Same-day results when sample collected by 11 AM
- Sample Type: 3 mL whole blood in Sodium Citrate tube
- Testing Method: Advanced Immunoturbidimetry
- Department: Specialized Coagulation Laboratory
- Expert Consultation: Board-certified Hematologists available
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, ensuring convenient access to advanced coagulation diagnostics. Our network includes fully-equipped laboratories in:
- New York City and surrounding metropolitan areas
- Los Angeles and Southern California regions
- Chicago and Illinois healthcare centers
- Houston and Texas medical facilities
- Phoenix and Arizona diagnostic centers
- Plus numerous additional locations nationwide
Take Control of Your Coagulation Health
Don’t let uncertainty about your clotting risk compromise your health and wellbeing. The Protein S Antigen Free Test provides definitive answers and empowers you with knowledge about your coagulation status. Our specialized hematology team stands ready to guide you through the testing process and help interpret your results within the context of your overall health picture.
Ready to schedule your Protein S Antigen Free Test? Contact our dedicated patient services team today at +1(267) 388-9828 or book your appointment online through our secure patient portal. Take the first step toward comprehensive coagulation assessment and personalized thrombophilia management.

