PRKG1 Gene Aortic Aneurysm Familial Thoracic Type 8 NGS Genetic DNA Test
Comprehensive Genetic Screening for Hereditary Aortic Conditions
The PRKG1 Gene Aortic Aneurysm Familial Thoracic Type 8 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic medicine, offering precise detection of mutations associated with familial thoracic aortic aneurysms. This advanced diagnostic tool utilizes next-generation sequencing technology to analyze the PRKG1 gene, which plays a critical role in vascular smooth muscle function and aortic wall integrity.
What This Test Measures and Detects
This sophisticated genetic analysis specifically targets:
- Pathogenic variants in the PRKG1 gene associated with familial thoracic aortic aneurysm type 8
- Single nucleotide polymorphisms (SNPs) affecting vascular smooth muscle contraction
- Genetic mutations that disrupt cyclic GMP-dependent protein kinase function
- Hereditary markers for progressive aortic dilation and dissection risk
- Inherited patterns of connective tissue vulnerability in the aortic wall
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Family history of thoracic aortic aneurysms or dissections
- Unexplained chest pain, back pain, or aortic dilation on imaging
- Connective tissue disorder symptoms without confirmed diagnosis
- Multiple family members with cardiovascular conditions
- Previous aortic surgery or intervention in family members
- Young-onset aortic conditions without traditional risk factors
Clinical Benefits of PRKG1 Genetic Testing
Undergoing this comprehensive genetic assessment provides numerous advantages:
- Early Risk Identification: Detect genetic predisposition before symptoms develop
- Personalized Monitoring: Establish appropriate screening intervals based on genetic risk
- Family Planning Guidance: Understand inheritance patterns for future generations
- Targeted Interventions: Implement preventive measures for at-risk individuals
- Reduced Anxiety: Provide clarity for families with hereditary aortic conditions
- Comprehensive Care Planning: Coordinate with cardiovascular specialists for optimal management
Understanding Your Test Results
Your genetic test results will fall into one of several categories:
- Positive Result: Indicates presence of a pathogenic PRKG1 mutation, requiring regular cardiovascular monitoring and potential preventive treatments
- Negative Result: No detected mutations, though continued monitoring may be recommended based on family history
- Variant of Uncertain Significance (VUS): Requires additional family studies and periodic re-evaluation as research advances
- Carrier Status: Important for family planning and understanding inheritance patterns
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | PRKG1 Gene Aortic Aneurysm Familial Thoracic Type 8 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Cardiovascular Genetics |
Pre-Test Requirements and Genetic Counseling
Before testing, we provide comprehensive genetic counseling services including:
- Detailed clinical history assessment for aortic aneurysm risk factors
- Construction of detailed family pedigree charts
- Education about test implications and potential outcomes
- Discussion of insurance coverage and financial considerations
- Coordination with referring physicians for integrated care
Nationwide Accessibility
We maintain testing facilities across major metropolitan areas throughout the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to advanced genetic testing regardless of your location.
Take Control of Your Cardiovascular Health
Don’t wait for symptoms to develop. Early genetic detection of PRKG1 mutations can significantly impact your long-term cardiovascular health and provide peace of mind for your entire family. Our experienced genetic counselors and cardiovascular specialists are ready to guide you through the testing process and help interpret your results within the context of your personal and family medical history.
Ready to schedule your PRKG1 genetic test? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic risk and implementing proactive cardiovascular health strategies.
