Prader-Willi Syndrome FISH Test – Comprehensive Genetic Diagnosis
Understanding Prader-Willi Syndrome FISH Testing
The Prader-Willi Syndrome FISH (Fluorescence In Situ Hybridization) Test represents a cutting-edge genetic diagnostic approach specifically designed to detect chromosomal abnormalities associated with Prader-Willi syndrome. This sophisticated molecular technique provides clinicians with precise information about the genetic basis of this complex neurodevelopmental disorder, enabling accurate diagnosis and informed treatment planning.
What Does the Prader-Willi Syndrome FISH Test Detect?
This specialized FISH test targets specific regions on chromosome 15, particularly the 15q11-q13 region, where genetic abnormalities responsible for Prader-Willi syndrome typically occur. The test can identify:
- Deletions in the paternal chromosome 15q11-q13 region
- Uniparental disomy (both chromosomes 15 inherited from the mother)
- Chromosomal translocations affecting the critical region
- Imprinting center defects that disrupt normal gene expression
Who Should Consider Prader-Willi Syndrome Testing?
This genetic test is recommended for individuals displaying characteristic symptoms of Prader-Willi syndrome, including:
- Infants with severe hypotonia (poor muscle tone) and feeding difficulties
- Children with developmental delays and cognitive impairments
- Individuals with hyperphagia (excessive eating) and obesity development
- Patients with hypogonadism and delayed puberty
- Children showing behavioral issues and obsessive-compulsive tendencies
- Individuals with short stature and small hands/feet
- Those with distinctive facial features associated with the syndrome
Clinical Benefits of Early Genetic Diagnosis
Obtaining a definitive genetic diagnosis through FISH testing provides numerous clinical advantages:
- Enables early intervention and specialized care planning
- Facilitates appropriate growth hormone therapy initiation
- Supports development of personalized nutritional management strategies
- Provides accurate genetic counseling for family planning
- Helps prevent obesity-related complications through early intervention
- Allows for targeted behavioral and educational support
Understanding Your Test Results
Our genetic specialists provide comprehensive interpretation of your FISH test results:
- Positive Result: Confirms genetic abnormalities consistent with Prader-Willi syndrome, enabling immediate implementation of appropriate management strategies
- Negative Result: Indicates absence of detectable chromosomal abnormalities in the tested regions, though additional testing may be recommended for complete evaluation
- Inconclusive Result: May require further genetic analysis using alternative methodologies for definitive diagnosis
Test Pricing and Sample Requirements
| Test Name | Regular Price | Discount Price |
|---|---|---|
| Prader-Willi Syndrome FISH Test | $176 USD | $132 USD |
Sample Types Accepted: Peripheral blood, Amniotic fluid, Chorionic villi, Cord blood
Turnaround Time: 3-4 days
Test Components: Sterile container, Sterile Normal Saline Container, Sodium heparin Vacutainer (2ml)
Pre-Test Instructions
The Prader-Willi Syndrome FISH test requires a doctor’s prescription for most cases. Prescription requirements do not apply for surgical cases, pregnancy-related testing, or individuals planning international travel. Our genetic counselors are available to discuss any pre-test concerns and ensure proper sample collection.
Nationwide Testing Availability
GGC DNA provides comprehensive Prader-Willi Syndrome FISH testing services across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories maintain the highest standards of genetic testing accuracy and reliability.
Take Action Today for Genetic Clarity
Don’t wait for uncertainty about genetic conditions to impact quality of life. Our experienced genetic specialists are ready to provide the answers you need through advanced FISH testing technology. Early diagnosis can significantly improve long-term outcomes and quality of life for individuals with Prader-Willi syndrome.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Prader-Willi Syndrome FISH test and take the first step toward genetic clarity and personalized care planning.
