PDGFR Mutation Screening Exons 12, 14, 18
Comprehensive Genetic Cancer Testing for Personalized Treatment
The PDGFR Mutation Screening for Exons 12, 14, and 18 represents a cutting-edge approach to genetic cancer diagnostics. This specialized test focuses on analyzing specific regions of the Platelet-Derived Growth Factor Receptor (PDGFR) gene, which plays a crucial role in cell growth, division, and survival. Mutations in these exons can lead to uncontrolled cell proliferation and are associated with various malignancies, making this screening essential for modern oncology practice.
What Does This Test Measure and Detect?
This advanced genetic screening specifically targets:
- Exon 12 mutations associated with gastrointestinal stromal tumors (GIST)
- Exon 14 alterations linked to various solid tumors
- Exon 18 mutations, particularly relevant for lung cancers and other malignancies
- Point mutations, insertions, and deletions within these critical gene regions
- Genetic variations that may respond to targeted tyrosine kinase inhibitors
Using sophisticated Sanger Sequencing technology, the test provides high-resolution analysis of tumor tissue samples, ensuring accurate detection of even subtle genetic changes that could impact treatment decisions.
Who Should Consider This Genetic Screening?
This test is particularly recommended for individuals experiencing:
- Diagnosed gastrointestinal stromal tumors (GIST) requiring treatment planning
- Suspected genetic cancer syndromes with family history
- Resistance to standard cancer therapies
- Need for targeted therapy selection
- Unexplained tumor growth patterns
- Planning for personalized cancer treatment approaches
Key Benefits of PDGFR Mutation Screening
Undergoing this comprehensive genetic analysis offers numerous advantages:
- Personalized Treatment Planning: Results guide selection of appropriate targeted therapies
- Improved Prognostic Information: Helps predict disease progression and treatment response
- Enhanced Therapeutic Outcomes: Increases likelihood of successful treatment with fewer side effects
- Family Risk Assessment: Provides insights into potential hereditary cancer risks
- Cost-Effective Care: Helps avoid ineffective treatments and associated expenses
Understanding Your Test Results
Your PDGFR Mutation Screening results will be carefully interpreted by our genetic specialists:
- Positive Result: Indicates the presence of specific mutations that may respond to targeted therapies
- Negative Result: Suggests absence of tested mutations, potentially indicating need for alternative treatment approaches
- Variant of Uncertain Significance: Some genetic changes may require additional clinical correlation
- Comprehensive Report: Includes detailed interpretation and clinical recommendations
All results are accompanied by expert consultation to ensure proper understanding and appropriate next steps.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $300 |
| Regular Price | $400 |
| Turnaround Time | 7-8 days |
| Sample Type | Tumor Tissue (Paraffin Embedded Blocks) |
| Testing Method | Sanger Sequencing |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Important Pre-Test Information
Please note that PDGFR Mutation Screening requires a doctor’s prescription for most cases. Prescription requirements do not apply to surgery and pregnancy cases or individuals planning international travel. Our team is available to assist with any prescription-related questions or concerns.
Take the Next Step Toward Personalized Cancer Care
Don’t leave your treatment decisions to chance. Our PDGFR Mutation Screening provides the genetic insights needed for informed, personalized cancer care. With rapid 7-8 day turnaround and comprehensive analysis, you’ll have the information necessary to work with your healthcare team on the most effective treatment strategy.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our genetic specialists are standing by to answer your questions and guide you through the testing process.
