Oncomine Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI) Test
Comprehensive Cancer Genetic Analysis for Personalized Treatment
The Oncomine TMB and MSI test represents a revolutionary advancement in precision oncology, providing critical insights into tumor genetics that guide immunotherapy treatment decisions. This sophisticated genetic analysis evaluates two key biomarkers that have transformed cancer care by enabling more targeted and effective treatment approaches.
What This Test Measures and Detects
This comprehensive test analyzes two crucial genetic markers:
- Tumor Mutation Burden (TMB): Measures the total number of mutations per megabase of DNA in tumor cells, indicating the tumor’s potential responsiveness to immunotherapy
- Microsatellite Instability (MSI): Assesses the stability of repetitive DNA sequences, identifying mismatch repair deficiencies that predict immunotherapy effectiveness
Using advanced Next-Generation Sequencing (NGS) and Sanger Sequencing technologies, the test provides a detailed genetic profile of tumor cells, helping oncologists make informed treatment decisions.
Who Should Consider This Test
This test is particularly valuable for patients with:
- Advanced or metastatic solid tumors considering immunotherapy
- Cancers with unclear treatment response predictions
- Rare or difficult-to-treat cancer types
- Patients who have failed conventional chemotherapy
- Those seeking personalized treatment options
- Individuals with family history of Lynch syndrome or hereditary cancers
Clinical Benefits and Importance
The Oncomine TMB and MSI test offers numerous advantages:
- Personalized Treatment Planning: Identifies patients most likely to benefit from immunotherapy
- Reduced Treatment Side Effects: Helps avoid ineffective treatments and unnecessary toxicity
- Improved Outcomes: Increases the likelihood of successful treatment response
- Comprehensive Genetic Insight: Provides multiple biomarker assessments in a single test
- Cost-Effective Care: Potentially reduces overall treatment costs by targeting effective therapies
Understanding Your Test Results
Your results will provide detailed information about:
- TMB Status: High TMB (≥10 mutations/megabase) suggests better immunotherapy response
- MSI Status: MSI-High indicates mismatch repair deficiency and predicts immunotherapy effectiveness
- Clinical Implications: Specific guidance on treatment options based on your genetic profile
- Next Steps: Recommendations for additional testing or treatment considerations
Our genetic counselors and oncology specialists will help you understand your results and discuss appropriate next steps for your cancer treatment journey.
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| Discount Price | $1312 |
| Regular Price | $1750 |
Test Specifications
- Turnaround Time: 2-3 weeks
- Sample Type: Tumor tissue + Peripheral Blood
- Test Components: Paraffin embedded tissue blocks + EDTA Vacutainer (3 ml)
- Methodology: NGS + Sanger Sequencing
Pre-Test Instructions
The Oncomine TMB and MSI test requires a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad. Please consult with your healthcare provider to determine if this test is appropriate for your specific situation.
Nationwide Availability
We have branches across all major cities in the USA, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality results regardless of your location.
Take Control of Your Cancer Treatment Journey
Don’t leave your treatment decisions to chance. The Oncomine TMB and MSI test provides the genetic insights needed to make informed decisions about your cancer care. With results available in 2-3 weeks and comprehensive support from our genetic specialists, you can approach your treatment with confidence and clarity.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your test or speak with our genetic counseling team. Take the first step toward personalized cancer treatment based on your unique genetic profile.
