NRAS Mutation Analysis Codons 12 & 13
Comprehensive Genetic Testing for Precision Cancer Care
The NRAS Mutation Analysis for codons 12 & 13 represents a cutting-edge genetic diagnostic tool that plays a pivotal role in modern oncology. This specialized test examines specific regions of the NRAS gene, which encodes a crucial protein involved in cellular signaling pathways that regulate growth, division, and survival. Mutations in codons 12 and 13 of the NRAS gene can lead to uncontrolled cell proliferation and are frequently associated with various cancer types, making this analysis essential for personalized cancer treatment strategies.
What Does the NRAS Mutation Analysis Detect?
This comprehensive genetic test specifically targets and identifies mutations occurring at codons 12 and 13 of the NRAS gene. These particular locations are hotspots for oncogenic mutations that result in constitutive activation of the RAS signaling pathway. The test utilizes advanced Sanger Sequencing technology to provide:
- Detection of specific point mutations in NRAS codons 12 and 13
- Identification of activating mutations that drive tumor growth
- Analysis of genetic alterations that impact treatment response
- Comprehensive mutation profiling for therapeutic decision-making
Who Should Consider NRAS Mutation Testing?
This genetic analysis is particularly important for patients with:
- Diagnosed melanoma requiring targeted therapy selection
- Colorectal cancer patients being evaluated for treatment options
- Hematological malignancies including certain leukemias
- Patients with thyroid cancer or other solid tumors
- Individuals with treatment-resistant cancers requiring alternative approaches
- Patients being considered for MEK inhibitor therapies
Clinical Benefits of NRAS Mutation Analysis
Undergoing NRAS Mutation Analysis provides numerous clinical advantages:
- Personalized Treatment Planning: Identifies patients who may benefit from specific targeted therapies
- Therapeutic Guidance: Helps determine appropriate MEK inhibitor eligibility
- Prognostic Information: Provides insights into disease progression and outcomes
- Clinical Trial Eligibility: May qualify patients for novel treatment protocols
- Comprehensive Cancer Management: Enhances overall treatment strategy development
Understanding Your Test Results
Your NRAS Mutation Analysis results will be carefully interpreted by our expert genetic specialists:
- Positive Result: Indicates the presence of NRAS mutations in codons 12 or 13, which may guide specific treatment recommendations and therapeutic approaches
- Negative Result: No detectable mutations found in the analyzed regions, suggesting alternative treatment strategies may be appropriate
- Inconclusive Result: May require additional testing or sample collection for definitive analysis
All results include detailed interpretation and clinical recommendations from our board-certified genetic counselors and oncology specialists.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | NRAS Mutation Analysis Codons 12 & 13 |
| Regular Price | $350 USD |
| Discount Price | $262 USD |
| Turnaround Time | 7-8 days |
| Sample Type | Tumor Tissue (Paraffin Embedded Tissue Blocks) |
| Testing Method | Sanger Sequencing |
Pre-Test Instructions and Requirements
The NRAS Mutation Analysis requires a doctor’s prescription for most clinical scenarios. However, prescription requirements do not apply to:
- Surgical procedure cases
- Pregnancy-related testing
- Individuals planning international travel
Our genetic counseling team is available to discuss testing indications and provide comprehensive pre-test guidance.
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take the Next Step in Your Cancer Care Journey
Don’t leave your treatment decisions to chance. The NRAS Mutation Analysis provides critical genetic information that can significantly impact your cancer treatment outcomes. Our team of oncology specialists and genetic counselors are ready to guide you through the testing process and help interpret your results for optimal treatment planning.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your NRAS Mutation Analysis and take control of your cancer care with precision genetic testing.
Book your comprehensive genetic assessment now and receive expert guidance on how these results can inform your personalized treatment strategy. Our dedicated patient care coordinators are available to answer your questions and facilitate the testing process from start to finish.

