MYEOV/IgH MM FISH Test: Comprehensive Genetic Analysis for Multiple Myeloma
Understanding the MYEOV/IgH MM FISH Test
The MYEOV/IgH MM FISH test represents a cutting-edge genetic diagnostic tool specifically designed for the evaluation and management of multiple myeloma. This sophisticated analysis utilizes fluorescence in situ hybridization (FISH) technology to detect specific chromosomal abnormalities that play a critical role in the development and progression of plasma cell disorders. As multiple myeloma continues to be a significant hematological malignancy, accurate genetic characterization has become increasingly important for personalized treatment approaches and prognostic assessment.
What Does the MYEOV/IgH MM Test Measure?
This specialized genetic test specifically targets and identifies the MYEOV/IgH translocation, a chromosomal rearrangement that occurs between the MYEOV gene on chromosome 11 and the immunoglobulin heavy chain (IgH) locus on chromosome 14. The detection of this specific genetic abnormality provides valuable insights into:
- Presence of high-risk genetic features in multiple myeloma
- Chromosomal instability patterns
- Genetic markers associated with disease aggressiveness
- Potential response to specific therapeutic agents
- Disease progression risk assessment
Who Should Consider the MYEOV/IgH MM Test?
This genetic analysis is particularly important for individuals experiencing symptoms or clinical findings suggestive of multiple myeloma or related plasma cell disorders. Consider this test if you present with:
- Unexplained bone pain, particularly in the back or ribs
- Persistent fatigue and weakness
- Recurrent infections or compromised immune function
- Elevated calcium levels in blood tests
- Anemia or other blood count abnormalities
- Kidney function impairment
- Abnormal protein levels detected in blood or urine tests
- Existing diagnosis of monoclonal gammopathy of undetermined significance (MGUS)
Clinical Indications and Benefits
The MYEOV/IgH MM FISH test offers numerous clinical advantages for patients and healthcare providers:
- Accurate Diagnosis: Provides definitive genetic evidence for multiple myeloma classification
- Prognostic Stratification: Helps determine disease aggressiveness and progression risk
- Treatment Guidance: Informs selection of targeted therapies and treatment intensity
- Disease Monitoring: Enables tracking of genetic changes over time
- Personalized Medicine: Supports development of individualized treatment plans
- Clinical Trial Eligibility: May qualify patients for specific research studies
Test Specifications and Requirements
The MYEOV/IgH MM FISH test utilizes advanced molecular techniques with specific sample requirements:
- Sample Type: Bone Marrow or Peripheral Blood
- Collection Tube: Sodium Heparin Vacutainer (2ml)
- Turnaround Time: 3-4 days
- Methodology: Fluorescence In Situ Hybridization (FISH)
Pre-Test Instructions
The MYEOV/IgH MM test requires a physician’s prescription for diagnostic purposes. Please note that prescription requirements do not apply to surgical cases, pregnancy-related testing, or individuals planning international travel. Our genetic counseling team is available to discuss any questions regarding test preparation or requirements.
Understanding Your Test Results
Interpreting MYEOV/IgH MM FISH test results requires specialized medical expertise. Your results will typically indicate:
- Positive Result: Detection of MYEOV/IgH translocation, indicating high-risk genetic features
- Negative Result: Absence of the specific translocation, suggesting standard-risk genetic profile
- Percentage of Abnormal Cells: Quantification of cells carrying the genetic abnormality
- Additional Genetic Findings: Any other chromosomal abnormalities detected
It is essential to discuss your results with your hematologist or oncologist, who will interpret them in the context of your overall clinical picture and guide appropriate treatment decisions.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $132 |
| Regular Price | $176 |
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with branches conveniently located in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and Philadelphia. Our network ensures that patients nationwide have access to this critical genetic testing service with consistent quality and rapid turnaround times.
Take Control of Your Health Journey
Early and accurate genetic characterization of multiple myeloma can significantly impact treatment outcomes and quality of life. The MYEOV/IgH MM FISH test provides the genetic insights necessary for informed medical decisions and personalized care planning.
Ready to schedule your MYEOV/IgH MM FISH test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions, discuss testing options, and guide you through the process with compassion and expertise.
Don’t wait to get the genetic information you need for optimal multiple myeloma management. Call now to schedule your comprehensive genetic assessment and take the first step toward personalized cancer care.

