MYD88 Gene Mutation Analysis
Understanding MYD88 Gene Mutation Analysis
The MYD88 Gene Mutation Analysis represents a cutting-edge genetic diagnostic tool that examines the MYD88 (Myeloid Differentiation Primary Response 88) gene for specific mutations. This gene encodes a critical adaptor protein involved in the Toll-like receptor and interleukin-1 receptor signaling pathways, playing a fundamental role in innate immune responses and inflammatory processes. When mutations occur in this gene, they can lead to dysregulated signaling that contributes to various hematological malignancies and autoimmune disorders.
What This Test Measures and Detects
The MYD88 Gene Mutation Analysis specifically targets and identifies:
- L265P mutation – the most common MYD88 mutation associated with lymphomas
- Other point mutations affecting the MYD88 gene structure
- Genetic alterations that impact Toll-like receptor signaling pathways
- Mutations that may influence treatment response and prognosis
Who Should Consider MYD88 Gene Mutation Testing
This genetic analysis is particularly recommended for individuals experiencing:
- Unexplained lymphadenopathy or enlarged lymph nodes
- Suspected or diagnosed Waldenström’s Macroglobulinemia
- Certain types of B-cell lymphomas, particularly diffuse large B-cell lymphoma
- Autoimmune conditions with suspected genetic components
- Family history of hematological malignancies
- Patients requiring targeted therapy selection
Clinical Benefits of MYD88 Mutation Analysis
Undergoing MYD88 Gene Mutation Analysis provides numerous clinical advantages:
- Accurate Diagnosis: Helps confirm specific lymphoma subtypes and autoimmune conditions
- Treatment Guidance: Informs targeted therapy decisions, including BTK inhibitor treatments
- Prognostic Information: Provides insights into disease progression and outcomes
- Personalized Medicine: Enables tailored treatment approaches based on genetic profile
- Family Risk Assessment: Helps evaluate genetic predisposition in family members
Understanding Your Test Results
Your MYD88 Gene Mutation Analysis results will provide clear information about:
- Positive Result: Indicates the presence of MYD88 mutations, which may guide specific treatment protocols and provide diagnostic confirmation
- Negative Result: Suggests absence of tested MYD88 mutations, though other genetic factors may still be involved
- Variant of Uncertain Significance: Rare genetic changes whose clinical significance requires further evaluation
All results should be discussed with your healthcare provider who can interpret them in the context of your complete medical history and clinical presentation.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | MYD88 Gene Mutation Analysis |
| Regular Price | $300 USD |
| Discount Price | $226 USD |
| Turnaround Time | 5-7 days |
| Sample Type | Peripheral blood/Tumor tissue |
| Test Components | EDTA Vacutainer (2ml)/Paraffin embedded tissue blocks |
| Testing Method | Sanger Sequencing |
Pre-Test Instructions and Requirements
The MYD88 Gene Mutation Analysis requires a Doctor’s prescription for testing. Please note that prescriptions are not applicable for surgery and pregnancy cases or individuals planning to travel abroad. Our experienced team will guide you through the sample collection process and ensure proper handling of your genetic material.
Nationwide Testing Availability
We have diagnostic branches conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Book Your MYD88 Gene Mutation Analysis Today
Take the first step toward understanding your genetic profile and optimizing your healthcare journey. Our dedicated genetic counselors and healthcare professionals are ready to assist you with scheduling, sample collection, and result interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your MYD88 Gene Mutation Analysis and take control of your genetic health with confidence and clarity.
