MT-TF Gene MELAS Syndrome NGS Genetic DNA Test
Comprehensive Mitochondrial DNA Analysis for MELAS Syndrome
The MT-TF Gene MELAS Syndrome NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying mitochondrial DNA mutations responsible for MELAS syndrome. This sophisticated genetic analysis utilizes next-generation sequencing technology to provide comprehensive insights into mitochondrial function and identify specific genetic variants that disrupt cellular energy production.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets the MT-TF gene, which encodes mitochondrial transfer RNA for phenylalanine. The test detects:
- Point mutations in the MT-TF gene, particularly the common m.583G>A mutation
- Other pathogenic variants affecting mitochondrial tRNA function
- Heteroplasmy levels (mixture of mutant and normal mitochondrial DNA)
- Mutation load that correlates with disease severity
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with:
- Unexplained stroke-like episodes in young adults
- Recurrent migraine headaches with neurological symptoms
- Progressive muscle weakness and exercise intolerance
- Seizures or epilepsy of unknown origin
- Developmental delays in children
- Sensorineural hearing loss
- Diabetes mellitus with neurological symptoms
- Family history of mitochondrial disorders
Clinical Benefits of MT-TF Gene Testing
Undergoing this comprehensive genetic analysis provides numerous clinical advantages:
- Accurate Diagnosis: Confirms MELAS syndrome and differentiates it from other mitochondrial disorders
- Family Planning: Enables genetic counseling for inheritance patterns and recurrence risks
- Personalized Treatment: Guides targeted therapeutic interventions and management strategies
- Prognostic Information: Helps predict disease progression and potential complications
- Early Intervention: Facilitates timely management to prevent serious complications
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert geneticists:
- Positive Result: Indicates the presence of pathogenic MT-TF gene mutations associated with MELAS syndrome
- Negative Result: Suggests absence of common MT-TF mutations, though other mitochondrial genes may need evaluation
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Heteroplasmy Level: Indicates the percentage of mutant mitochondrial DNA, which correlates with symptom severity
Test Pricing Information
| Test Name | Discount Price | Regular Price |
|---|---|---|
| MT-TF Gene MELAS Syndrome NGS Genetic DNA Test | $500 USD | $700 USD |
Nationwide Testing Availability
We have conveniently located testing centers across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Take Control of Your Health Today
Don’t let unexplained neurological symptoms compromise your quality of life. Our comprehensive MT-TF Gene MELAS Syndrome NGS Genetic DNA Test provides the answers you need for proper diagnosis and management. Our genetic counselors are available to discuss your results and provide personalized recommendations.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or book your test online. Take the first step toward understanding your genetic health and receiving the specialized care you deserve.
