MDM2 Gene Amplification Test: Advanced Cancer Biomarker Detection
Understanding the MDM2 Gene Amplification Test
The MDM2 Gene Amplification Test represents a cutting-edge molecular diagnostic approach that plays a pivotal role in modern oncology practice. This specialized test utilizes Fluorescence In Situ Hybridization (FISH) technology to detect amplification of the MDM2 (Mouse Double Minute 2) gene, which serves as a critical biomarker in cancer diagnosis and classification.
MDM2 is a proto-oncogene located on chromosome 12q15 that encodes a protein involved in regulating the tumor suppressor p53. When amplified, MDM2 can lead to uncontrolled cell growth and tumor development, making its detection essential for accurate cancer diagnosis and appropriate treatment planning.
What the MDM2 Test Measures and Detects
The MDM2 Gene Amplification Test specifically identifies:
- Gene amplification events in the MDM2 locus
- Chromosomal abnormalities involving chromosome 12q15
- Genetic markers associated with specific tumor types
- Molecular signatures that help differentiate between benign and malignant tumors
Using FISH technology, the test provides precise visualization of gene copy numbers within tumor cells, offering valuable insights into the molecular characteristics of the tissue sample.
Who Should Consider MDM2 Testing
This test is particularly important for individuals with:
- Suspected soft tissue tumors requiring precise classification
- Lipomatous tumors where differentiation between benign and malignant forms is challenging
- Patients with atypical lipomatous tumors/well-differentiated liposarcomas
- Cases where dedifferentiated liposarcoma is suspected
- Individuals with recurrent tumors requiring molecular characterization
- Patients being evaluated for targeted therapy options
Clinical Benefits of MDM2 Testing
Undergoing MDM2 gene amplification testing provides numerous advantages:
- Accurate Diagnosis: Helps distinguish between benign lipomas and malignant liposarcomas
- Treatment Guidance: Informs appropriate therapeutic strategies based on molecular findings
- Prognostic Information: Provides valuable insights into disease behavior and potential outcomes
- Therapeutic Targeting: Identifies patients who may benefit from specific targeted therapies
- Surgical Planning: Assists in determining appropriate surgical margins and approaches
- Monitoring: Enables tracking of disease progression and treatment response
Understanding Your MDM2 Test Results
Your MDM2 test results will provide critical information about the genetic characteristics of your tumor tissue:
Normal Results
No significant MDM2 gene amplification detected, which may suggest benign conditions or different tumor types.
Positive Results
Detection of MDM2 gene amplification typically indicates:
- Well-differentiated liposarcoma/atypical lipomatous tumor
- Dedifferentiated liposarcoma
- Other tumors with 12q15 amplification
Clinical Interpretation
Your healthcare provider will interpret the results in the context of your clinical presentation, imaging findings, and other diagnostic tests to develop a comprehensive treatment plan.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | MDM2 Gene Amplification Test |
| Regular Price | $300 USD |
| Discount Price | $226 USD |
| Turnaround Time | 7-8 Days |
| Sample Type | Tumor Tissue |
| Test Components | Paraffin Embedded Tissue Blocks |
| Methodology | FISH (Fluorescence In Situ Hybridization) |
Pre-Test Instructions
The MDM2 Gene Amplification Test requires a doctor’s prescription for most cases. Please note that prescriptions are not applicable for surgical procedures, pregnancy cases, or individuals planning international travel. Our team will guide you through the sample collection and submission process.
Nationwide Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our extensive network ensures accessible testing services for patients nationwide.
Take Control of Your Health Today
Don’t let uncertainty about your diagnosis delay your treatment. The MDM2 Gene Amplification Test provides the critical molecular information needed for accurate cancer diagnosis and personalized treatment planning. Our experienced oncology genetics team is ready to assist you with this advanced diagnostic testing.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your MDM2 Gene Amplification Test and take the first step toward precise cancer diagnosis and targeted treatment.
With our discounted price of $226 USD and comprehensive nationwide coverage, accessing this advanced genetic testing has never been more convenient. Trust our expertise in oncology genetics to provide you with accurate, reliable results that can make a significant difference in your healthcare journey.
