Maternal Serum Screen 2 Advanced Reflex to Maternal Blood for Fetal DNA MBFD Chromosome 21 Test
Comprehensive Prenatal Screening for Chromosomal Abnormalities
The Maternal Serum Screen 2 Advanced Reflex to MBFD-21 Test represents a cutting-edge approach to prenatal care, combining traditional serum screening with advanced DNA analysis technology. This comprehensive screening protocol is designed to provide expectant mothers with the most accurate and reliable information about their baby’s chromosomal health during the crucial first trimester.
What This Advanced Screening Test Measures
This sophisticated prenatal screening evaluates multiple biomarkers and genetic components to assess fetal health:
- PAPP-A (Pregnancy-Associated Plasma Protein-A): A protein produced by the placenta that helps assess fetal development
- Free Beta HCG: A hormone that provides important information about placental function
- Risk Evaluation Algorithm: Advanced software analysis combining maternal factors with biomarker levels
- MBFD-21 DNA Analysis: Non-invasive prenatal testing for Trisomy 21 (Down syndrome) through maternal blood sample
Who Should Consider This Advanced Prenatal Screening
This comprehensive screening is recommended for all pregnant women, with particular importance for:
- Women aged 35 years or older at delivery
- Patients with a family history of chromosomal abnormalities
- Previous pregnancy affected by Trisomy 21 or other chromosomal disorders
- Abnormal ultrasound findings suggesting increased risk
- IVF pregnancies or those with assisted reproductive technology
- Women with diabetes or other medical conditions affecting pregnancy
- Smokers or those with specific lifestyle factors
Clinical Benefits of Advanced Reflex Screening
Early Detection and Peace of Mind
The reflex testing protocol offers significant advantages over traditional screening methods. When initial serum screening indicates elevated risk, the test automatically proceeds to MBFD-21 DNA analysis without requiring additional patient visits or sample collection. This streamlined approach reduces anxiety and provides definitive results more quickly.
Enhanced Accuracy and Reliability
By combining biochemical markers with DNA analysis, this screening achieves detection rates exceeding 99% for Down syndrome with very low false-positive rates. The dual-methodology approach minimizes unnecessary invasive procedures while maximizing detection accuracy.
Understanding Your Test Results
Interpreting Screening Outcomes
Your results will fall into one of several categories, each with specific implications for your pregnancy management:
- Low-Risk Result: Indicates a very low probability of chromosomal abnormalities, providing reassurance for continued routine prenatal care
- Screen-Positive with Reflex to MBFD-21: When initial screening suggests elevated risk, the test automatically proceeds to DNA analysis for definitive results
- High-Risk MBFD-21 Result: Indicates increased likelihood of Trisomy 21, requiring consultation with genetic counseling and consideration of diagnostic testing
- Inconclusive Results: Rare cases where additional testing or follow-up may be recommended
Next Steps After Testing
All results should be discussed with your healthcare provider, who can provide personalized guidance based on your specific situation. Our genetic counseling services are available to help you understand your results and make informed decisions about your pregnancy care.
Test Pricing and Availability
| Test Component | Price Type | Amount (USD) |
|---|---|---|
| Maternal Serum Screen 2 Advanced Reflex to MBFD-21 | Discount Price | $88 |
| Maternal Serum Screen 2 Advanced Reflex to MBFD-21 | Regular Price | $126 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Schedule Your Advanced Prenatal Screening Today
Take the next step in ensuring your baby’s health with our comprehensive prenatal screening program. Our experienced team is ready to provide you with the highest quality care and accurate results you can trust.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Maternal Serum Screen 2 Advanced Reflex to MBFD-21 Test. Our knowledgeable staff will answer your questions, help you understand the testing process, and coordinate your appointment at a location convenient for you.
Don’t wait to get the peace of mind you deserve during this important time. Early detection through advanced screening provides valuable information to guide your pregnancy journey and ensure the best possible outcomes for you and your baby.

