Maternal Cell Contamination MCC Test
Understanding Maternal Cell Contamination Testing
The Maternal Cell Contamination (MCC) Test represents a critical quality control measure in prenatal genetic diagnostics. This specialized assessment detects and quantifies the presence of maternal cells within fetal samples obtained through procedures like chorionic villus sampling (CVS) or amniocentesis. When maternal cells contaminate fetal samples, they can significantly compromise the accuracy of genetic testing results, potentially leading to misdiagnosis or false reassurance.
Why MCC Testing Matters
Maternal cell contamination occurs when maternal tissue inadvertently mixes with fetal samples during collection. This contamination can mask fetal genetic abnormalities or create false positive results, ultimately affecting clinical decisions regarding pregnancy management. The MCC test serves as an essential safeguard, ensuring that genetic analysis reflects the true fetal genotype rather than a contaminated mixture.
What the MCC Test Detects
The Maternal Cell Contamination Test specifically identifies:
- Presence of maternal DNA in fetal samples
- Percentage of contamination levels
- Sample purity for accurate genetic analysis
- Potential sources of false results in prenatal testing
Using advanced molecular techniques, the test distinguishes between maternal and fetal genetic material, providing quantitative data about contamination levels. This information allows genetic laboratories to determine whether samples are suitable for comprehensive genetic analysis or require additional processing.
Who Should Consider MCC Testing
Primary Candidates Include:
- Women undergoing chorionic villus sampling (CVS) procedures
- Patients scheduled for amniocentesis testing
- Individuals with previous inconclusive prenatal genetic results
- Patients where sample quality concerns exist
- Women with increased risk factors for genetic disorders
- Those requiring confirmation of prenatal testing accuracy
Clinical Indications:
Healthcare providers typically recommend MCC testing when:
- Initial genetic testing shows ambiguous results
- Sample collection involved technical challenges
- High-risk pregnancy conditions are present
- Previous testing revealed potential contamination issues
- Comprehensive genetic analysis is planned
Benefits of Maternal Cell Contamination Testing
Enhanced Diagnostic Accuracy
The MCC test significantly improves the reliability of prenatal genetic diagnoses by ensuring that results reflect true fetal genetics rather than contaminated samples. This accuracy is crucial for making informed decisions about pregnancy management and potential interventions.
Risk Mitigation
By identifying contamination early, the test prevents:
- False negative results for genetic conditions
- Incorrect chromosomal abnormality diagnoses
- Unnecessary medical interventions
- Delayed appropriate care
Quality Assurance
The test provides laboratories with essential quality control data, supporting:
- Validation of testing methodologies
- Confidence in result interpretation
- Compliance with laboratory standards
- Continuous improvement of testing protocols
Understanding Your MCC Test Results
Interpretation Guidelines
Test results typically indicate the percentage of maternal cell contamination present in the sample:
- Low Contamination (0-5%): Samples are generally considered acceptable for genetic analysis with minimal impact on result accuracy.
- Moderate Contamination (6-20%): May require additional analysis or interpretation caution, particularly for certain genetic conditions.
- High Contamination (>20%): Significant risk of inaccurate results; sample may need recollection or specialized analysis.
Clinical Implications
Your healthcare provider will discuss how contamination levels affect your specific genetic testing results. In cases of significant contamination, additional testing or sample recollection may be recommended to ensure diagnostic accuracy.
Test Pricing Information
| Test Description | Price (USD) |
|---|---|
| Maternal Cell Contamination MCC Test |
Discount Price: $138 |
Nationwide Availability
We have diagnostic centers across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Schedule Your MCC Test Today
Ensure the accuracy of your prenatal genetic testing with our comprehensive Maternal Cell Contamination assessment. Our experienced genetic counselors and laboratory specialists are ready to provide you with reliable, timely results that support informed healthcare decisions.
Call or WhatsApp us now at +1(267) 388-9828 to book your test or schedule a consultation. Take the essential step toward accurate prenatal diagnosis and peace of mind during your pregnancy journey.

