Lung Cancer Panel 6: Comprehensive Genetic Analysis for Personalized Treatment
Understanding Lung Cancer Genetic Testing
The Lung Cancer Panel 6 represents a cutting-edge approach to molecular diagnostics in oncology, specifically designed to identify key genetic alterations that drive non-small cell lung cancer (NSCLC) progression. This comprehensive panel combines three essential testing methodologies to provide a complete genetic profile of lung cancer tumors, enabling oncologists to make informed treatment decisions based on the specific molecular characteristics of each patient’s cancer.
What This Test Measures and Detects
Our advanced Lung Cancer Panel 6 utilizes multiple sophisticated techniques to analyze critical genetic markers:
EGFR Mutation Analysis by Sequencing
This component employs Sanger sequencing technology to detect mutations in the Epidermal Growth Factor Receptor (EGFR) gene. EGFR mutations are present in approximately 10-15% of NSCLC patients in the United States and are particularly common in non-smokers, women, and individuals of Asian descent. Identifying these mutations is crucial as they predict response to EGFR tyrosine kinase inhibitors.
ALK Rearrangement Detection by IHC
Using immunohistochemistry (IHC), this test identifies ALK gene rearrangements, which occur in about 3-7% of NSCLC cases. ALK-positive lung cancers respond exceptionally well to ALK inhibitors, making this detection vital for treatment selection.
ROS1 Fusion Analysis by FISH
Fluorescence in situ hybridization (FISH) technology detects ROS1 gene fusions, present in approximately 1-2% of NSCLC patients. ROS1 rearrangements define a distinct molecular subset of lung cancer that responds to specific targeted therapies.
Who Should Consider This Test
This comprehensive genetic panel is recommended for patients who:
- Have been diagnosed with non-small cell lung cancer
- Are experiencing persistent cough, chest pain, or breathing difficulties
- Have unexplained weight loss or fatigue with respiratory symptoms
- Show abnormal findings on chest imaging studies
- Have a family history of lung cancer or genetic predisposition
- Are current or former smokers with concerning symptoms
- Need treatment planning for advanced or metastatic lung cancer
Benefits of Comprehensive Lung Cancer Genetic Testing
Undergoing the Lung Cancer Panel 6 provides numerous advantages for patients and healthcare providers:
- Personalized Treatment Selection: Identifies specific genetic alterations to guide targeted therapy choices
- Improved Treatment Outcomes: Matches patients with therapies most likely to be effective
- Reduced Side Effects: Avoids ineffective treatments and their associated toxicities
- Comprehensive Analysis: Multiple testing methods ensure thorough genetic profiling
- Clinical Trial Eligibility: Helps identify patients for specific targeted therapy trials
- Prognostic Information: Provides insights into disease behavior and potential outcomes
Understanding Your Test Results
Your Lung Cancer Panel 6 results will provide detailed information about the genetic status of your tumor:
Positive Results
A positive result indicates the presence of specific genetic alterations that may respond to targeted therapies. Your oncologist will discuss appropriate treatment options based on the specific mutations detected.
Negative Results
A negative result means the tested genetic alterations were not detected. This information is still valuable as it helps exclude certain treatment options and may guide consideration of alternative therapeutic approaches.
Interpretation and Next Steps
All results should be discussed with your healthcare provider in the context of your overall clinical picture. Our genetic counselors are available to help explain complex results and their implications for your treatment journey.
Test Pricing and Information
| Test Component | Price |
|---|---|
| Lung Cancer Panel 6 (EGFR, ALK, ROS1) | Regular Price: $1000 USD |
| Current Discount Price | $750 USD |
| Turnaround Time | 5-7 days |
| Sample Type | Tumor tissue (paraffin embedded blocks) |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing results regardless of location.
Take Control of Your Lung Cancer Journey
Understanding the genetic profile of your lung cancer is the first step toward personalized, effective treatment. Our comprehensive Lung Cancer Panel 6 provides the critical information needed to make informed decisions about your care. With rapid turnaround times and expert genetic analysis, we’re committed to supporting you through every step of your diagnostic journey.
Ready to schedule your test? Call our dedicated patient services team today at +1(267) 388-9828 to book your appointment or speak with one of our genetic counselors about whether this test is right for you.
Note: This test requires a doctor’s prescription for most cases. Prescription requirements do not apply to surgery and pregnancy cases or individuals planning international travel. Our team can assist with the prescription process if needed.
