LRRC8A Gene Agammaglobulinemia Type 5 Autosomal Recessive NGS Genetic DNA Test
Comprehensive Genetic Testing for Primary Immunodeficiency Disorders
The LRRC8A Gene Agammaglobulinemia Type 5 Autosomal Recessive NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for primary immunodeficiency conditions. This advanced genetic analysis specifically targets the LRRC8A gene, which plays a crucial role in B-cell development and antibody production. When mutations occur in this gene through autosomal recessive inheritance patterns, individuals develop Agammaglobulinemia Type 5 – a serious immune deficiency characterized by extremely low levels of immunoglobulins and increased susceptibility to infections.
What This Test Measures and Detects
Our state-of-the-art Next Generation Sequencing (NGS) technology comprehensively analyzes the entire LRRC8A gene to identify:
- Pathogenic variants and mutations in the LRRC8A gene
- Autosomal recessive inheritance patterns
- Single nucleotide polymorphisms (SNPs) affecting gene function
- Insertions, deletions, and copy number variations
- Novel genetic variants with potential clinical significance
Who Should Consider This Genetic Test
This specialized genetic test is recommended for individuals presenting with:
- Recurrent bacterial infections, particularly respiratory and gastrointestinal
- Persistent low immunoglobulin levels (IgG, IgA, IgM)
- Family history of primary immunodeficiency disorders
- Unexplained failure to thrive in infants and children
- Autoimmune manifestations alongside immune deficiency symptoms
- Consanguineous parentage with immune-related health concerns
Clinical Benefits of LRRC8A Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous clinical advantages:
- Definitive Diagnosis: Confirms Agammaglobulinemia Type 5 with molecular precision
- Family Planning Guidance: Identifies carrier status and recurrence risks
- Personalized Treatment: Enables targeted immunoglobulin replacement therapy
- Proactive Management: Facilitates early intervention and infection prevention
- Genetic Counseling: Provides expert interpretation and family risk assessment
Understanding Your Test Results
Our comprehensive genetic counseling service helps you interpret your LRRC8A test results:
- Positive Result: Identifies pathogenic variants confirming Agammaglobulinemia Type 5 diagnosis
- Carrier Status: Detects single mutated copy in asymptomatic individuals
- Negative Result: No LRRC8A mutations detected, suggesting alternative diagnoses
- Variant of Uncertain Significance: Requires additional family studies for interpretation
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | LRRC8A Gene Agammaglobulinemia Type 5 Autosomal Recessive NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) |
Pre-Test Requirements and Genetic Counseling
Before testing, we recommend:
- Comprehensive clinical history documentation
- Professional genetic counseling session
- Detailed pedigree chart creation of affected family members
- Discussion of potential outcomes and implications
- Informed consent process
Nationwide Accessibility Across USA
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take Control of Your Genetic Health Today
Don’t let uncertainty about your immune health continue. Our LRRC8A genetic test provides the clarity needed for proper diagnosis and management of Agammaglobulinemia Type 5. With our discounted price of $500 USD and comprehensive genetic counseling support, you can make informed decisions about your health and family planning.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your genetic counseling session and book your LRRC8A Gene Agammaglobulinemia Type 5 Autosomal Recessive NGS Genetic DNA Test. Our expert genetic counselors are ready to guide you through every step of the testing process and help you understand your results with compassion and clinical expertise.
