Limb-Girdle Muscular Dystrophy LGMD Genetic Test
Comprehensive Genetic Analysis for Muscular Dystrophy Diagnosis
Limb-Girdle Muscular Dystrophy (LGMD) represents a diverse group of inherited muscle disorders characterized by progressive weakness and wasting of muscles primarily in the hips and shoulders. Our advanced LGMD genetic test provides comprehensive analysis using next-generation sequencing technology to identify specific genetic mutations responsible for this condition. Early and accurate diagnosis is crucial for implementing appropriate management strategies and improving quality of life for affected individuals.
What This Test Measures and Detects
Our comprehensive LGMD panel analyzes five critical genes associated with various forms of limb-girdle muscular dystrophy:
- SGCA Gene: Associated with LGMD type 2D, encoding alpha-sarcoglycan protein
- SGCB Gene: Linked to LGMD type 2E, encoding beta-sarcoglycan protein
- SGCD Gene: Responsible for LGMD type 2F, encoding delta-sarcoglycan protein
- SGCG Gene: Associated with LGMD type 2C, encoding gamma-sarcoglycan protein
- FKRP Gene: Connected to LGMD type 2I, encoding fukutin-related protein
This test utilizes cutting-edge Next-Generation Sequencing (NGS) technology to detect point mutations, small insertions/deletions, and copy number variations in these genes, providing comprehensive genetic insights for accurate diagnosis.
Who Should Consider This Genetic Test
This test is recommended for individuals experiencing symptoms suggestive of limb-girdle muscular dystrophy, including:
- Progressive muscle weakness in hips, thighs, and shoulders
- Difficulty rising from chairs or climbing stairs
- Frequent falls and balance problems
- Waddling gait or walking on toes
- Muscle cramps and stiffness
- Family history of muscular dystrophy or unexplained muscle weakness
- Elevated creatine kinase levels in blood tests
- Children or adults with delayed motor milestones
Key Benefits of LGMD Genetic Testing
Undergoing genetic testing for limb-girdle muscular dystrophy offers numerous advantages:
- Accurate Diagnosis: Provides definitive identification of the specific LGMD subtype
- Personalized Treatment: Enables targeted management strategies based on genetic findings
- Family Planning: Offers crucial information for genetic counseling and reproductive decisions
- Proactive Management: Allows early intervention to slow disease progression
- Clinical Trial Eligibility: May qualify patients for specific research studies and emerging therapies
- Psychological Relief: Reduces uncertainty and provides clear answers about symptoms
Understanding Your Test Results
Our comprehensive genetic analysis provides detailed insights into your LGMD status:
- Positive Result: Identifies specific genetic mutations confirming LGMD diagnosis, enabling subtype classification and personalized management
- Negative Result: May rule out common LGMD subtypes but doesn’t exclude all forms of muscular dystrophy
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation and family studies
- Carrier Status: Determines if you carry a single copy of a mutated gene, important for family planning
All results include detailed interpretation by our board-certified genetic counselors and neurologists, with recommendations for next steps and management strategies.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | Limb-Girdle Muscular Dystrophy LGMD Genetic Test |
| Regular Price | $426 USD |
| Discount Price | $350 USD |
| Turnaround Time | 21 days |
| Sample Type | Blood |
| Methodology | Next-Generation Sequencing (NGS) |
| Department | Molecular Diagnostics |
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures accessible genetic testing services for patients throughout the country.
Take Control of Your Health Today
Don’t let uncertainty about muscle weakness symptoms affect your quality of life. Our comprehensive LGMD genetic test provides the answers you need for proper diagnosis and management. Early genetic identification can significantly impact treatment outcomes and quality of life.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or speak with our genetic counseling team. Take the first step toward understanding your genetic health and developing an effective management plan for muscular dystrophy concerns.
