LAMB1 Gene Lissencephaly Type 5 NGS Genetic DNA Test
Comprehensive Genetic Testing for Brain Development Disorders
The LAMB1 Gene Lissencephaly Type 5 NGS Genetic DNA Test represents a significant advancement in pediatric neurology and genetic diagnostics. This specialized test focuses on identifying mutations in the LAMB1 gene, which plays a crucial role in brain development and cortical organization. Lissencephaly type 5 is a rare neurological condition characterized by smooth brain surface due to impaired neuronal migration during fetal development.
What Does This Test Measure?
This comprehensive genetic analysis utilizes Next-Generation Sequencing (NGS) technology to examine the complete coding region of the LAMB1 gene. The test specifically detects:
- Point mutations and small insertions/deletions in the LAMB1 gene
- Genetic variants associated with lissencephaly type 5
- Mutations affecting laminin subunit beta-1 protein function
- Pathogenic variants that disrupt normal brain cortex development
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with:
- Infants with developmental delays and neurological abnormalities
- Children exhibiting seizure disorders of unknown origin
- Patients with abnormal brain imaging showing smooth brain surface
- Individuals with family history of lissencephaly or brain malformations
- Cases of unexplained intellectual disability in pediatric patients
- Suspected cases of cortical development disorders
Key Benefits of LAMB1 Genetic Testing
- Accurate Diagnosis: Provides definitive identification of LAMB1 gene mutations
- Early Intervention: Enables timely medical management and therapeutic strategies
- Family Planning: Offers crucial information for genetic counseling and reproductive decisions
- Personalized Care: Guides targeted treatment approaches based on genetic findings
- Prognostic Information: Helps predict disease progression and potential complications
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert geneticists and neurologists:
- Positive Result: Indicates the presence of pathogenic LAMB1 gene mutation, confirming lissencephaly type 5 diagnosis
- Negative Result: Suggests absence of detectable LAMB1 mutations, though other genetic causes may need investigation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical impact requires further evaluation
- Carrier Status: May identify individuals carrying the mutation without showing symptoms
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | LAMB1 Gene Lissencephaly Type 5 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history of the patient
- Genetic counseling session to create family pedigree chart
- Documentation of family members affected by LAMB1-related conditions
- Recent neurological evaluations and brain imaging studies
Nationwide Accessibility
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Take the Next Step Toward Diagnosis
If you or your loved one is experiencing symptoms suggestive of lissencephaly or other brain development disorders, don’t delay in seeking genetic answers. Our expert team of genetic counselors and pediatric neurologists is ready to guide you through the testing process and provide comprehensive support.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your LAMB1 Gene Lissencephaly Type 5 NGS Genetic DNA Test and take the first step toward accurate diagnosis and personalized care.
