KRAS NRAS Mutation Analysis: Comprehensive Genetic Testing for Cancer Treatment
Understanding KRAS NRAS Genetic Testing
The KRAS NRAS Mutation Analysis represents a cutting-edge approach to personalized cancer medicine, providing critical insights into the genetic drivers of tumor growth and progression. These specific genetic markers play a pivotal role in determining treatment responsiveness and guiding therapeutic decisions for various cancer types.
What Are KRAS and NRAS Genes?
KRAS and NRAS belong to the RAS family of genes, which encode proteins that regulate cell growth, division, and survival. When mutations occur in these genes, they can become permanently “switched on,” leading to uncontrolled cell proliferation and cancer development. Understanding the mutation status of these genes is essential for modern oncology practice.
What the Test Measures and Detects
This comprehensive genetic analysis specifically targets:
- Point mutations in codons 12, 13, and 61 of the KRAS gene
- Similar critical mutations in the NRAS gene
- Genetic alterations that affect response to targeted therapies
- Mutations that may indicate treatment resistance
Advanced Sanger Sequencing Technology
Our test utilizes Sanger sequencing, the gold standard for mutation detection, providing highly accurate and reliable results. This method ensures precise identification of genetic variations with exceptional sensitivity and specificity.
Who Should Consider KRAS NRAS Testing
This test is particularly valuable for:
- Patients diagnosed with colorectal cancer considering anti-EGFR therapy
- Individuals with non-small cell lung cancer requiring treatment planning
- Patients with melanoma being evaluated for targeted treatments
- Those experiencing treatment resistance or disease progression
- Individuals with strong family history of RAS-related cancers
Clinical Indications and Symptoms
Patients presenting with confirmed cancer diagnoses, particularly those involving the gastrointestinal tract, lungs, or skin, should discuss this testing with their oncologist. Early genetic profiling can significantly impact treatment success and long-term outcomes.
Benefits of KRAS NRAS Mutation Analysis
- Personalized Treatment Selection: Identifies patients who will benefit from specific targeted therapies
- Avoid Unnecessary Treatment: Prevents administration of ineffective medications and associated side effects
- Improved Outcomes: Enables selection of the most appropriate treatment strategy
- Cost-Effective Care: Reduces healthcare costs by avoiding ineffective treatments
- Comprehensive Cancer Management: Provides valuable prognostic information
Understanding Your Test Results
Your KRAS NRAS mutation analysis results will fall into one of several categories:
Mutation Detected
If mutations are identified in either KRAS or NRAS genes, this indicates that certain targeted therapies may be less effective. Your healthcare provider will discuss alternative treatment options that may be more appropriate for your specific genetic profile.
No Mutation Detected
A negative result suggests that targeted therapies directed against EGFR may be effective. This information helps your medical team select the most promising treatment approach.
Inconclusive Results
In rare cases, results may be inconclusive due to sample quality or technical factors. Your healthcare provider will discuss whether retesting is necessary.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | KRAS NRAS Mutation Analysis |
| Regular Price | $600 USD |
| Discount Price | $450 USD |
| Turnaround Time | 7-8 days |
| Sample Type | Tumor tissue (Paraffin embedded tissue blocks) |
| Testing Method | Sanger Sequencing |
Pre-Test Instructions
KRAS NRAS testing requires a Doctor’s prescription. Please note that prescriptions are not applicable for surgery and pregnancy cases or individuals planning to travel abroad. Consult with your healthcare provider to determine if this test is appropriate for your situation.
Nationwide Testing Availability
We have branches across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, and many other cities. Our nationwide network ensures convenient access to advanced genetic testing services.
Take Control of Your Cancer Treatment Journey
Understanding your genetic profile is the first step toward personalized cancer care. The KRAS NRAS Mutation Analysis provides critical information that can significantly impact your treatment success and quality of life.
Ready to Get Started?
Don’t leave your treatment decisions to chance. Contact us today to schedule your KRAS NRAS genetic testing and take an active role in your cancer care journey.
Call or WhatsApp: +1(267) 388-9828
Our genetic specialists are available to answer your questions and help you understand how this testing can benefit your specific situation. Take the first step toward personalized cancer treatment today.
