IRAK4 Gene Invasive Pneumococcal Disease Recurrent Isolated Type 1 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Immune Deficiency Disorders
The IRAK4 Gene Invasive Pneumococcal Disease Recurrent Isolated Type 1 NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for individuals suffering from recurrent invasive pneumococcal infections. This advanced genetic test specifically targets mutations in the IRAK4 (Interleukin-1 Receptor-Associated Kinase 4) gene, which plays a critical role in innate immune responses against bacterial pathogens, particularly Streptococcus pneumoniae.
What Does This Test Measure?
This sophisticated diagnostic examination utilizes Next-Generation Sequencing (NGS) technology to comprehensively analyze the IRAK4 gene for:
- Point mutations affecting protein function
- Insertions and deletions disrupting gene expression
- Single nucleotide polymorphisms compromising immune signaling
- Structural variations impacting Toll-like receptor pathways
- Genetic variants affecting interleukin-1 receptor signaling
Clinical Indications: Who Should Consider This Test?
This genetic test is particularly recommended for individuals presenting with:
- Recurrent invasive pneumococcal disease episodes
- Multiple episodes of pneumococcal meningitis or bacteremia
- Family history of recurrent pneumococcal infections
- Unexplained severe pneumococcal disease in childhood
- Poor response to pneumococcal vaccination
- Consanguineous parents with affected relatives
- Early-onset invasive bacterial infections
Key Benefits of IRAK4 Genetic Testing
- Accurate Diagnosis: Provides definitive genetic confirmation of IRAK4 deficiency
- Personalized Treatment: Guides targeted antibiotic prophylaxis strategies
- Family Planning: Enables informed reproductive decisions through genetic counseling
- Early Intervention: Facilitates prompt medical management to prevent complications
- Comprehensive Analysis: Utilizes advanced NGS technology for thorough genetic assessment
- Improved Outcomes: Supports development of individualized therapeutic approaches
Understanding Your Test Results
Your genetic test report will provide detailed information about IRAK4 gene variations:
- Positive Result: Identifies pathogenic mutations confirming IRAK4 deficiency, requiring specialized immunology consultation and targeted management
- Negative Result: No disease-causing mutations detected, suggesting alternative causes for recurrent infections
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation and family studies
- Carrier Status: Identifies individuals with single copy mutations who may pass the condition to offspring
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | IRAK4 Gene Invasive Pneumococcal Disease Recurrent Isolated Type 1 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Immunology, Genetics, Dermatology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation of recurrent pneumococcal infections
- Genetic counseling session to create detailed family pedigree
- Discussion of test implications with healthcare provider
- Understanding of potential outcomes and management options
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our comprehensive network ensures accessible genetic testing services for patients nationwide.
Take Control of Your Health Today
Don’t let recurrent infections compromise your quality of life. Our advanced IRAK4 genetic testing provides the answers you need for proper diagnosis and targeted treatment. Early genetic identification can significantly improve health outcomes and prevent serious complications.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic predisposition and developing an effective management strategy for recurrent pneumococcal disease.
