Inv(16) AML M4Eo FISH Test: Comprehensive Genetic Analysis for Acute Myeloid Leukemia
Understanding the Inv(16) AML M4Eo Genetic Test
The Inv(16) AML M4Eo FISH Test represents a cutting-edge diagnostic approach in modern oncology, specifically designed to detect the inversion of chromosome 16 that characterizes acute myeloid leukemia subtype M4Eo. This sophisticated genetic analysis utilizes fluorescence in situ hybridization (FISH) technology to provide precise identification of chromosomal abnormalities that drive leukemia development and progression.
What This Test Measures and Detects
This specialized genetic test specifically targets and identifies:
- Inversion of chromosome 16 (inv(16)(p13.1q22))
- Formation of the CBFB-MYH11 fusion gene
- Genetic markers associated with AML M4Eo subtype
- Chromosomal rearrangements critical for diagnosis and prognosis
Who Should Consider This Test?
This genetic screening is particularly important for individuals experiencing:
- Unexplained fatigue and weakness that persists
- Frequent infections or slow recovery from illnesses
- Easy bruising or unusual bleeding patterns
- Pale skin or shortness of breath
- Bone pain or tenderness
- Unexplained weight loss or loss of appetite
- Abnormal blood cell counts in routine testing
Clinical Indications and Symptoms
Patients presenting with symptoms suggestive of acute myeloid leukemia, particularly those with abnormal peripheral blood counts or bone marrow findings, should strongly consider this test. The Inv(16) abnormality is specifically associated with acute myelomonocytic leukemia with eosinophilia (AML M4Eo), making this test essential for accurate subtype classification.
Benefits of Taking the Inv(16) AML M4Eo Test
- Accurate Diagnosis: Provides definitive identification of specific genetic abnormalities
- Personalized Treatment: Guides targeted therapy decisions based on genetic profile
- Prognostic Information: Helps predict disease course and treatment response
- Early Detection: Enables prompt intervention and improved outcomes
- Monitoring Capability: Allows tracking of treatment effectiveness
- Comprehensive Analysis: Uses advanced FISH technology for reliable results
Scientific Importance and Clinical Relevance
The detection of inv(16) is clinically significant because this specific genetic abnormality defines a distinct subtype of AML with unique biological characteristics and treatment responses. Patients with this genetic marker often respond well to specific chemotherapy regimens, making accurate identification crucial for optimal treatment planning.
Understanding Your Test Results
Your Inv(16) AML M4Eo FISH test results will provide clear information about:
- Positive Result: Indicates presence of the inv(16) abnormality, confirming AML M4Eo diagnosis
- Negative Result: Suggests absence of this specific genetic marker
- Interpretation Guidance: Detailed explanation of what your results mean for your diagnosis and treatment
- Next Steps: Recommendations for additional testing or treatment planning
Test Specifications and Requirements
Sample Type: Bone Marrow / Peripheral blood
Test Components: Sodium Heparin Vacutainer (2ml)
Turnaround Time: 3-4 days
Pre-test Instructions: This test requires a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $132 |
| Regular Price | $176 |
Nationwide Availability
We have branches across the United States, including all major metropolitan areas. Our state-of-the-art facilities in New York, Los Angeles, Chicago, Houston, Phoenix, and other key locations ensure convenient access to this essential genetic testing service.
Take Control of Your Health Today
Don’t wait to get the answers you need for proper diagnosis and treatment planning. Our experienced genetic specialists are ready to provide comprehensive testing and support throughout your diagnostic journey.
Book Your Test Today: Call or WhatsApp us at +1(267) 388-9828 to schedule your Inv(16) AML M4Eo FISH test and take the first step toward accurate diagnosis and personalized treatment.
Our dedicated team is committed to providing you with reliable genetic testing services, clear result interpretation, and compassionate support throughout your healthcare journey. Trust General Genetics Corporation for accurate, timely, and comprehensive genetic analysis.
