Immunohistochemistry Synaptophysin Test
Understanding the Immunohistochemistry Synaptophysin Test
The Immunohistochemistry Synaptophysin Test represents a cornerstone in modern cancer diagnostics, specifically designed to detect neuroendocrine tumors through advanced molecular staining techniques. This sophisticated laboratory procedure utilizes specific antibodies to identify synaptophysin, a crucial protein marker found in neuroendocrine cells and their corresponding tumors. As a vital component of comprehensive cancer evaluation, this test provides oncologists and pathologists with essential information for accurate diagnosis and targeted treatment planning.
What Does the Test Measure?
The Immunohistochemistry Synaptophysin Test specifically detects the presence and distribution of synaptophysin protein within tissue samples. Synaptophysin serves as a reliable marker for neuroendocrine differentiation, making it invaluable for:
- Identifying neuroendocrine tumors and their cellular origins
- Distinguishing between different types of cancer with similar appearances
- Confirming neuroendocrine differentiation in poorly differentiated tumors
- Assisting in tumor classification and grading systems
- Providing crucial information for treatment selection and prognosis
Who Should Consider This Test?
This specialized diagnostic test is recommended for patients presenting with symptoms or clinical findings suggestive of neuroendocrine tumors, including:
- Patients with unexplained hormonal syndromes or endocrine abnormalities
- Individuals with abnormal imaging findings suggesting neuroendocrine tumors
- Patients with suspected carcinoid tumors, pancreatic neuroendocrine tumors, or small cell lung cancer
- Those requiring confirmation of neuroendocrine differentiation in biopsy specimens
- Patients undergoing evaluation for metastatic tumors of unknown origin
- Individuals with family history of neuroendocrine disorders
Clinical Indications and Symptoms
Common clinical scenarios that warrant Synaptophysin testing include:
- Flushing, diarrhea, and wheezing characteristic of carcinoid syndrome
- Unexplained hypoglycemia or hyperglycemia
- Abdominal pain with gastrointestinal symptoms
- Respiratory symptoms with suspected lung neuroendocrine tumors
- Multiple endocrine neoplasia syndromes
- Metastatic disease with unknown primary origin
Benefits of Synaptophysin Testing
Choosing the Immunohistochemistry Synaptophysin Test offers numerous advantages for both patients and healthcare providers:
- Accurate Diagnosis: Provides definitive identification of neuroendocrine tumors
- Treatment Guidance: Helps oncologists select appropriate targeted therapies
- Prognostic Information: Assists in predicting disease course and outcomes
- Comprehensive Evaluation: Complements other diagnostic modalities for complete assessment
- Early Detection: Enables timely intervention and improved survival rates
- Personalized Medicine: Supports development of individualized treatment plans
Understanding Your Test Results
Interpreting Synaptophysin test results requires professional medical expertise, but general guidance includes:
- Positive Result: Indicates presence of synaptophysin, suggesting neuroendocrine differentiation
- Negative Result: Absence of synaptophysin staining, typically ruling out neuroendocrine origin
- Focal Positivity: May indicate partial neuroendocrine differentiation in mixed tumors
- Intensity Patterns: Strong vs weak staining can provide additional diagnostic information
- Correlation Required: Results should always be interpreted alongside clinical findings and other tests
Your healthcare provider will discuss the specific implications of your results and develop an appropriate management plan based on the comprehensive diagnostic picture.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $76 |
| Regular Price | $112 |
Turnaround Time and Sample Requirements
Our laboratory maintains efficient processing with the following turnaround times:
- Sample Collection: Daily by 6 PM
- Block Processing: 5 days
- Tissue Biopsy: 5 days
- Large Complex Tissue: 7 days
Sample Submission Guidelines
For optimal results, please submit:
- Tumor tissue preserved in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Ship samples at room temperature with proper packaging
- Include complete clinical documentation including histopathology report
- Provide detailed biopsy site information and relevant clinical history
- Ensure proper labeling and patient identification on all specimens
Nationwide Accessibility
We proudly serve patients across the United States with comprehensive diagnostic services. Our network includes specialized testing facilities in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. No matter where you’re located, advanced cancer diagnostics are within reach.
Book Your Test Today
Take the first step toward accurate diagnosis and effective treatment planning. Our experienced team is ready to assist you with scheduling, sample collection coordination, and answering any questions about the Immunohistochemistry Synaptophysin Test.
Call us now at +1(267) 388-9828 to schedule your test or speak with our medical specialists. We’re committed to providing accessible, reliable, and timely diagnostic services to support your healthcare journey.
Don’t delay crucial diagnostic testing – early detection through advanced immunohistochemistry can significantly impact treatment outcomes and quality of life. Trust our expertise in neuroendocrine tumor diagnostics and take control of your health today.
