Immunohistochemistry pS2 Test: Advanced Breast Cancer Biomarker Analysis
Understanding the Immunohistochemistry pS2 Test
The Immunohistochemistry pS2 Test represents a cutting-edge diagnostic approach in breast cancer management. This specialized laboratory procedure detects the presence and distribution of pS2 protein within breast tissue samples, providing crucial information about tumor characteristics and potential treatment responses. As a key biomarker in breast cancer pathology, pS2 testing has revolutionized how oncologists approach personalized cancer care and treatment planning.
What Does the pS2 Test Measure?
The Immunohistochemistry pS2 Test specifically measures the expression levels of pS2 protein, also known as Trefoil Factor 1 (TFF1). This protein serves as an important indicator of estrogen receptor activity in breast cancer cells. The test provides:
- Detection of pS2 protein presence and distribution
- Assessment of estrogen receptor pathway activation
- Evaluation of tumor differentiation status
- Prediction of hormone therapy responsiveness
- Prognostic information for breast cancer outcomes
Who Should Consider This Test?
The Immunohistochemistry pS2 Test is recommended for individuals in specific clinical situations:
- Patients newly diagnosed with breast cancer
- Individuals with suspicious breast lesions requiring characterization
- Patients considering hormone therapy options
- Those needing prognostic information for treatment planning
- Individuals with recurrent breast cancer requiring updated biomarker analysis
Clinical Indications and Symptoms
This test is particularly valuable for patients experiencing:
- Recent breast cancer diagnosis
- Abnormal mammogram findings
- Palpable breast masses requiring characterization
- Family history of breast cancer
- Need for personalized treatment strategy development
Benefits of pS2 Testing
Choosing the Immunohistochemistry pS2 Test offers numerous advantages for breast cancer management:
- Personalized Treatment Planning: Guides selection of appropriate hormone therapies
- Prognostic Information: Provides insights into likely disease progression
- Therapy Response Prediction: Helps anticipate how tumors may respond to treatment
- Comprehensive Cancer Profiling: Complements other biomarker testing
- Evidence-Based Decisions: Supports informed treatment choices
Understanding Your Test Results
Interpreting pS2 test results requires professional medical expertise, but general guidance includes:
- Positive pS2 Expression: Indicates estrogen receptor pathway activation and potential responsiveness to hormone therapy
- Negative pS2 Expression: Suggests limited benefit from hormone-based treatments
- Variable Expression Patterns: May indicate heterogeneous tumor characteristics
- Quantitative Assessment: The intensity and distribution of staining provide additional prognostic information
Your healthcare provider will discuss your specific results in the context of your overall clinical picture and other diagnostic findings.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $46 |
| Regular Price | $52 |
Turnaround Time and Sample Requirements
Our laboratory maintains efficient processing standards:
- Sample Submission: Daily by 6 PM
- Report Timeline: Block: 5 days | Tissue Biopsy: 5 days | Tissue Large Complex: 7 days
- Sample Type: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Shipping: Room temperature
- Required Documentation: Histopathology report, biopsy site information, and clinical history
Nationwide Testing Availability
GGC DNA maintains testing facilities across the United States, with branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible, reliable testing services for patients throughout the country.
Book Your Test Today
Take the next step in your breast cancer management journey with the Immunohistochemistry pS2 Test. Our experienced team of oncologists and pathologists are ready to provide comprehensive testing and support. Contact us today to schedule your test and gain valuable insights into your breast cancer profile.
Call or WhatsApp: +1(267) 388-9828
Our dedicated healthcare professionals are available to answer your questions, discuss testing options, and help you schedule your appointment at your convenience.

