Immunohistochemistry CD45 LCA Test: Comprehensive Cancer Diagnosis
Understanding the Immunohistochemistry CD45 LCA Test
The Immunohistochemistry CD45 LCA Test represents a cornerstone in modern cancer diagnostics, specifically designed to detect the CD45 leukocyte common antigen. This sophisticated laboratory technique utilizes specialized antibodies to identify the presence of CD45, a protein expressed on the surface of virtually all hematopoietic cells. The test’s importance lies in its ability to distinguish between different types of malignancies, particularly in cases where the origin of tumor cells remains uncertain.
Immunohistochemistry (IHC) has revolutionized cancer diagnosis by allowing pathologists to visualize specific cellular markers within tissue samples. The CD45 LCA test specifically targets the leukocyte common antigen, which serves as a reliable marker for cells of hematopoietic origin. This precision enables healthcare providers to make more accurate diagnoses and develop targeted treatment strategies.
What the CD45 LCA Test Measures and Detects
The Immunohistochemistry CD45 LCA Test specifically measures the presence and distribution of the CD45 antigen within tissue samples. This comprehensive detection includes:
- Hematopoietic Cell Identification: Confirms whether cells originate from blood-forming tissues
- Lymphoma vs. Carcinoma Differentiation: Helps distinguish between lymphoid malignancies and epithelial cancers
- Leukocyte Lineage Confirmation: Identifies cells belonging to white blood cell lineages
- Tumor Origin Determination: Provides critical information about whether tumors arise from hematopoietic or non-hematopoietic tissues
The test’s sensitivity allows for detection even in small tissue samples, making it invaluable for biopsy specimens where tissue quantity may be limited.
Who Should Consider the CD45 LCA Test?
This specialized diagnostic test is particularly important for individuals presenting with:
- Unexplained Lymphadenopathy: Patients with enlarged lymph nodes of unknown origin
- Suspected Hematologic Malignancies: Individuals with symptoms suggesting lymphoma, leukemia, or related disorders
- Undifferentiated Tumors: Cases where the cellular origin of a tumor remains unclear after initial evaluation
- Metastatic Disease of Unknown Primary: Patients with cancer spread where the original site cannot be identified
- Abnormal Blood Cell Counts: Individuals with unexplained changes in white blood cell populations
Clinical Benefits of CD45 LCA Testing
Choosing the Immunohistochemistry CD45 LCA Test provides numerous clinical advantages:
- Accurate Diagnosis: Enables precise identification of hematopoietic versus non-hematopoietic tumors
- Treatment Guidance: Informs appropriate therapeutic approaches based on tumor type
- Prognostic Information: Helps predict disease course and potential outcomes
- Therapeutic Monitoring: Assists in evaluating treatment response and disease progression
- Minimized Misdiagnosis: Reduces the risk of incorrect cancer classification
Understanding Your Test Results
Interpreting CD45 LCA test results requires professional medical expertise, but general guidance includes:
- Positive Result: Indicates the presence of CD45 antigen, suggesting hematopoietic origin of cells
- Negative Result: Suggests the absence of CD45, typically indicating non-hematopoietic tumor origin
- Variable Staining Patterns: Different intensity and distribution patterns may provide additional diagnostic information
- Clinical Correlation: Results must be interpreted in context with other clinical and pathological findings
Your healthcare provider will discuss the specific implications of your test results and how they inform your diagnosis and treatment plan.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry CD45 LCA Test | $76 USD | $112 USD |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Action for Your Health
Don’t leave your diagnosis to chance. The Immunohistochemistry CD45 LCA Test provides the clarity needed for accurate cancer diagnosis and appropriate treatment planning. Our experienced team of pathologists and oncologists are ready to assist you with comprehensive testing and expert interpretation.
Book your test today by calling +1(267) 388-9828 or schedule your appointment online. Take the first step toward definitive diagnosis and personalized treatment.
Note: Turnaround times vary by sample type – Block: 5 days, Tissue Biopsy: 5 days, Tissue large complex: 7 days. Samples accepted daily by 6 pm. Please provide a copy of your Histopathology report, biopsy site information, and clinical history with your sample.

