Immunohistochemistry CD35 Test: Advanced Cancer Detection
Understanding the Immunohistochemistry CD35 Test
The Immunohistochemistry CD35 Test represents a cutting-edge diagnostic approach in modern oncology and pathology. This specialized laboratory technique utilizes antibodies to detect the presence of CD35 antigens, also known as complement receptor 1 (CR1), within tissue samples. CD35 plays a vital role in the immune system’s complement pathway and serves as a crucial marker for identifying specific cell types in various pathological conditions, particularly cancer.
Immunohistochemistry (IHC) has revolutionized cancer diagnosis by allowing pathologists to visualize specific proteins within tissue sections. The CD35 test specifically targets this important membrane protein, which is expressed on various immune cells including B lymphocytes, follicular dendritic cells, and certain epithelial cells. Understanding CD35 expression patterns provides invaluable insights into tumor biology and helps guide targeted treatment approaches.
What the CD35 Test Measures and Detects
The Immunohistochemistry CD35 Test precisely measures the presence, distribution, and intensity of CD35 protein expression in tissue specimens. This sophisticated analysis reveals:
- Presence of CD35 antigens in tumor cells
- Pattern and intensity of CD35 expression
- Cellular localization of CD35 markers
- Distribution across different tissue compartments
- Quantitative assessment of protein expression levels
CD35 detection is particularly valuable in distinguishing between different types of lymphomas, identifying follicular dendritic cell tumors, and characterizing certain hematological malignancies. The test provides critical information that helps differentiate between benign and malignant conditions, enabling more accurate diagnosis and classification.
Who Should Consider the CD35 Test
This specialized diagnostic test is recommended for patients presenting with specific clinical scenarios and symptoms:
Clinical Indications
- Patients with suspected hematological malignancies
- Individuals with unexplained lymph node enlargement
- Patients with abnormal blood cell counts
- Cases requiring differential diagnosis of lymphoma subtypes
- Suspected follicular dendritic cell tumors
- Evaluation of tumor tissue for CD35 expression patterns
Symptoms and Conditions
- Persistent unexplained fever and night sweats
- Unexplained weight loss and fatigue
- Enlarged lymph nodes that persist for weeks
- Abnormal blood test results suggesting hematological disorders
- Suspected immune system disorders affecting complement pathways
Benefits of Taking the Immunohistochemistry CD35 Test
Choosing the CD35 test provides numerous advantages for patients and healthcare providers:
Diagnostic Precision
- Accurate identification of specific cancer subtypes
- Enhanced diagnostic confidence for complex cases
- Differentiation between similar-looking tumor types
- Comprehensive characterization of tumor biology
Treatment Guidance
- Informs targeted therapy selection
- Helps predict treatment response
- Guides personalized treatment approaches
- Supports clinical decision-making for complex cases
Prognostic Value
- Provides insights into disease progression
- Helps assess treatment effectiveness
- Supports long-term disease monitoring
- Enables better patient outcome predictions
Understanding Your Test Results
Interpreting CD35 test results requires specialized expertise from pathologists and oncologists. Here’s a general guide to understanding your findings:
Positive CD35 Expression
A positive result indicates the presence of CD35 markers in the tested tissue. This finding can help confirm specific diagnoses such as follicular dendritic cell sarcomas, certain lymphomas, or other CD35-positive tumors. The pattern and intensity of staining provide additional diagnostic information that your healthcare provider will interpret in clinical context.
Negative CD35 Expression
A negative result suggests the absence of significant CD35 expression in the examined tissue. This finding helps exclude certain diagnoses and may point toward alternative conditions. Negative results are equally valuable in the diagnostic process, as they help narrow down potential diagnoses.
Interpretation Considerations
- Results are interpreted in conjunction with other clinical findings
- Pattern and intensity of staining provide diagnostic clues
- Results help guide further diagnostic testing if needed
- Final diagnosis integrates multiple test results and clinical information
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry CD35 Test | $76 USD | $112 USD |
Nationwide Availability and Testing Process
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, and Philadelphia. Our state-of-the-art laboratories ensure consistent, high-quality testing standards nationwide.
Turnaround Time
- Sample Processing: Daily by 6 PM
- Standard Tissue Block: 5 days
- Tissue Biopsy: 5 days
- Complex Tissue Samples: 7 days
Sample Requirements
Submit tumor tissue preserved in 10% formal-saline OR formalin-fixed paraffin-embedded blocks. Ship samples at room temperature with proper documentation including:
- Complete histopathology report
- Specific biopsy site information
- Detailed clinical history
Take Action for Your Health
Don’t wait to get the answers you need for proper diagnosis and treatment. Our experienced team of pathologists and laboratory specialists are ready to provide you with accurate, reliable results. Early and accurate diagnosis is crucial for effective cancer management and improved outcomes.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Immunohistochemistry CD35 Test. Our knowledgeable staff will guide you through the process, answer your questions, and help you take the next step toward better health.
With convenient locations across the USA and competitive pricing, accessing advanced cancer diagnostics has never been easier. Trust General Genetics Corporation for your diagnostic needs and take control of your health journey today.
