Immunohistochemistry CD34 Test: Advanced Cancer Diagnostic Marker Analysis
Understanding the Immunohistochemistry CD34 Test
The Immunohistochemistry CD34 Test represents a cutting-edge diagnostic approach in modern oncology and pathology. This specialized laboratory procedure utilizes advanced immunohistochemical techniques to detect the presence of CD34, a transmembrane glycoprotein that serves as a crucial marker for hematopoietic stem cells and vascular endothelial cells. The test’s precision and reliability make it an indispensable tool for accurate cancer diagnosis and classification.
CD34 plays a fundamental role in cell adhesion and migration, making its detection particularly valuable in identifying tumors of vascular origin. When tissue samples are processed through this test, specific antibodies bind to CD34 antigens, creating visible markers that pathologists can analyze under microscopy. This process provides critical insights into tumor composition and behavior, enabling healthcare providers to make informed treatment decisions.
What the CD34 Test Detects and Measures
The Immunohistochemistry CD34 Test specifically identifies and quantifies the expression of CD34 protein in tissue specimens. This sophisticated analysis reveals:
- Presence of endothelial cells in vascular tumors
- Identification of hematopoietic stem cell populations
- Detection of gastrointestinal stromal tumors (GISTs)
- Characterization of dermatofibrosarcoma protuberans
- Analysis of Kaposi sarcoma markers
- Evaluation of angiosarcoma development
- Assessment of vascular malformations
- Detection of epithelioid hemangioendothelioma
Clinical Applications and Diagnostic Value
This test serves multiple critical functions in cancer diagnosis and management. It helps differentiate between various soft tissue tumors, identifies the vascular nature of malignancies, and assists in determining tumor aggressiveness. The CD34 marker’s presence or absence provides valuable prognostic information that directly impacts treatment planning and patient outcomes.
Who Should Consider the CD34 Test?
The Immunohistochemistry CD34 Test is recommended for patients presenting with specific clinical scenarios and symptoms:
- Patients with suspected vascular tumors or malignancies
- Individuals with unexplained skin lesions or masses
- Patients diagnosed with gastrointestinal stromal tumors
- Those with suspected Kaposi sarcoma or angiosarcoma
- Individuals requiring differential diagnosis of soft tissue tumors
- Patients with abnormal bleeding or vascular abnormalities
- Those undergoing cancer staging and characterization
- Individuals with recurrent or metastatic disease requiring precise identification
Symptoms and Clinical Indicators
Patients experiencing unexplained skin nodules, persistent bleeding, rapidly growing masses, or those with family history of vascular cancers should discuss CD34 testing with their healthcare provider. Early detection through this specialized test can significantly improve treatment success rates and patient prognosis.
Benefits of CD34 Immunohistochemistry Testing
Choosing the Immunohistochemistry CD34 Test provides numerous advantages for both patients and healthcare providers:
- Accurate Diagnosis: Provides definitive identification of tumor types and origins
- Treatment Guidance: Helps oncologists develop targeted treatment strategies
- Prognostic Information: Offers insights into disease progression and outcomes
- Minimally Invasive: Utilizes existing biopsy samples without additional procedures
- Comprehensive Analysis: Provides detailed cellular and molecular information
- Fast Results: Delivers critical diagnostic information within 5-7 days
- Cost-Effective: Affordable testing at only $76 USD with comprehensive coverage
Understanding Your Test Results
Interpreting CD34 test results requires professional medical expertise, but understanding the general implications can help patients participate in their care decisions:
Positive CD34 Expression
A positive result indicates the presence of CD34 markers in the tested tissue. This typically suggests:
- Vascular origin of the tumor
- Presence of endothelial cell proliferation
- Possible diagnosis of specific sarcoma types
- Need for further specialized testing and evaluation
Negative CD34 Expression
A negative result suggests the absence of CD34 markers, which may indicate:
- Non-vascular tumor origin
- Differentiation from CD34-positive malignancies
- Alternative diagnostic possibilities
- Requirement for additional marker testing
Clinical Correlation
Your healthcare provider will correlate CD34 results with clinical findings, imaging studies, and other laboratory tests to establish a comprehensive diagnosis. The CD34 test represents one piece of the diagnostic puzzle that, when combined with other information, provides a complete clinical picture.
Test Pricing and Availability
| Test Description | Regular Price | Discount Price |
|---|---|---|
| Immunohistochemistry CD34 Test | $112 USD | $76 USD |
Turnaround Time and Sample Requirements
Our laboratory processes samples daily by 6 PM with the following turnaround times:
- Block samples: 5 days
- Tissue biopsy: 5 days
- Tissue large complex: 7 days
Sample Requirements: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Availability and Convenient Testing
General Genetics Corporation provides comprehensive CD34 testing services across the United States. We have established branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures that patients receive consistent, high-quality testing regardless of location.
Easy Sample Submission Process
Our streamlined submission process makes testing convenient for both patients and healthcare providers. We accept samples from licensed medical facilities and provide detailed instructions for proper sample handling and transportation to ensure test accuracy and reliability.
Take Action for Your Health Today
Don’t let uncertainty about your diagnosis delay necessary treatment. The Immunohistochemistry CD34 Test provides the critical information needed for accurate cancer diagnosis and appropriate treatment planning. With our affordable pricing and rapid turnaround times, you can get the answers you need quickly and confidently.
Ready to schedule your test? Contact us today:
Phone: +1(267) 388-9828
Our dedicated team is available to answer your questions, assist with scheduling, and provide guidance throughout the testing process. Take the first step toward accurate diagnosis and effective treatment by booking your Immunohistochemistry CD34 Test today.
Note: This test requires physician authorization and proper clinical documentation. Please consult with your healthcare provider to determine if CD34 testing is appropriate for your specific medical situation.
