Immunohistochemistry CD10 Test: Advanced Cancer Detection and Classification
Understanding the Immunohistochemistry CD10 Test
The Immunohistochemistry CD10 Test represents a cutting-edge diagnostic approach in modern oncology that utilizes specific antibody-antigen interactions to detect the presence of CD10 markers in tissue samples. CD10, also known as neutral endopeptidase or common acute lymphoblastic leukemia antigen (CALLA), is a cell surface metalloproteinase that plays a crucial role in cancer diagnosis and classification. This sophisticated laboratory technique provides invaluable information for pathologists and oncologists in identifying tumor origins, determining cancer subtypes, and developing personalized treatment strategies.
What Does the CD10 Test Measure?
The Immunohistochemistry CD10 Test specifically detects and visualizes the presence of CD10 antigen expression in tissue specimens. This test measures:
- Presence and distribution of CD10 markers in tumor cells
- Intensity of CD10 expression patterns
- Cellular localization of CD10 antigens
- Percentage of positive tumor cells
- Pattern of staining (membranous, cytoplasmic, or both)
Who Should Consider This Test?
The Immunohistochemistry CD10 Test is recommended for patients with:
- Suspected renal cell carcinoma or kidney tumors
- Undiagnosed metastatic cancers of unknown primary origin
- Acute lymphoblastic leukemia (ALL) diagnosis and monitoring
- Suspected endometrial stromal sarcomas
- Mesenchymal tumors requiring precise classification
- Patients with abnormal imaging findings suggesting specific cancer types
- Individuals requiring differential diagnosis between similar-appearing tumors
Clinical Indications and Symptoms
Patients experiencing symptoms such as unexplained weight loss, persistent fatigue, abnormal bleeding, palpable masses, or abnormal laboratory findings should discuss this test with their healthcare provider. The test is particularly valuable when:
- Conventional pathology cannot definitively identify tumor type
- Metastatic cancer is detected without known primary site
- Treatment planning requires precise tumor classification
- Monitoring treatment response in known CD10-positive cancers
Benefits of the Immunohistochemistry CD10 Test
Choosing the Immunohistochemistry CD10 Test provides numerous advantages for accurate cancer management:
- Precise Diagnosis: Enables accurate identification of specific cancer types
- Treatment Guidance: Helps oncologists select appropriate targeted therapies
- Prognostic Information: Provides insights into disease progression and outcomes
- Differential Diagnosis: Distinguishes between morphologically similar tumors
- Minimally Invasive: Utilizes existing tissue samples without additional procedures
- Cost-Effective: Provides critical diagnostic information at an affordable price
Scientific Methodology
Our Immunohistochemistry CD10 Test employs state-of-the-art laboratory techniques including antigen retrieval, specific monoclonal antibody binding, and advanced visualization systems. The process involves careful tissue preparation, controlled antibody incubation, and precise interpretation by board-certified pathologists to ensure accurate and reliable results.
Understanding Your Test Results
Your Immunohistochemistry CD10 Test results will be interpreted by experienced pathologists and typically fall into these categories:
- Positive Result: Indicates CD10 antigen expression, supporting diagnoses such as renal cell carcinoma, acute lymphoblastic leukemia, or specific sarcoma types
- Negative Result: Absence of CD10 staining, which may help exclude certain tumor types or suggest alternative diagnoses
- Focal Positivity: Limited CD10 expression that requires correlation with other markers and clinical findings
- Variable Intensity: Different staining patterns that provide additional diagnostic information
It’s essential to discuss your results with your healthcare provider, who will interpret them in the context of your complete medical history, symptoms, and other diagnostic findings. Positive CD10 staining does not automatically confirm a specific diagnosis but provides valuable information for your medical team.
Test Pricing and Availability
| Test Name | Regular Price | Discount Price |
|---|---|---|
| Immunohistochemistry CD10 Test | $112 USD | $88 USD |
Turnaround Time and Sample Requirements
We offer efficient testing with the following turnaround times:
- Block Samples: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
- Sample Acceptance: Daily by 6 PM
Sample Type Required: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Availability
GGC DNA has testing facilities and collection centers across the United States, serving patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures convenient access to advanced diagnostic testing regardless of your location.
Book Your Test Today
Take control of your health with the advanced diagnostic capabilities of the Immunohistochemistry CD10 Test. Our team of specialists is ready to provide you with accurate, reliable results to guide your treatment journey. Contact us today to schedule your test or speak with one of our genetic counselors.
Call or WhatsApp: +1(267) 388-9828
Don’t wait for answers – get the precise diagnostic information you need to make informed decisions about your health. Our compassionate team is here to support you every step of the way with expert testing, clear communication, and comprehensive care.

