ALK D5F3 Immunohistochemistry Test: Advanced Cancer Detection
Understanding the ALK D5F3 Immunohistochemistry Test
The ALK D5F3 Immunohistochemistry Test represents a breakthrough in molecular diagnostics for cancer detection and treatment planning. This sophisticated laboratory procedure specifically identifies abnormal ALK (Anaplastic Lymphoma Kinase) protein expression patterns in tumor tissue samples. The test utilizes the highly specific D5F3 monoclonal antibody, which offers exceptional sensitivity and specificity in detecting ALK gene rearrangements that drive certain types of cancer development and progression.
Immunohistochemistry (IHC) has revolutionized cancer diagnostics by enabling pathologists to visualize specific protein markers within tissue samples. The ALK D5F3 test builds upon this foundation, providing clinicians with critical information about the molecular characteristics of tumors that directly influence treatment decisions and patient outcomes.
What the ALK D5F3 Test Measures and Detects
The ALK D5F3 Immunohistochemistry Test specifically detects:
- ALK protein overexpression resulting from gene rearrangements
- Abnormal ALK fusion proteins in cancer cells
- Specific ALK-positive tumor subtypes
- Molecular markers for targeted therapy eligibility
- Prognostic indicators for treatment response
This test is particularly valuable for identifying the approximately 3-7% of non-small cell lung cancer (NSCLC) patients who harbor ALK rearrangements. The detection of these genetic abnormalities opens the door to highly effective targeted therapies that specifically inhibit ALK signaling pathways.
Who Should Consider the ALK D5F3 Test
Clinical Indications and Symptoms
This test is recommended for patients with:
- Newly diagnosed non-small cell lung cancer
- Advanced or metastatic lung adenocarcinoma
- Younger patients with lung cancer (typically under 50 years)
- Light or never-smokers with lung cancer
- Patients with anaplastic large cell lymphoma
- Inflammatory myofibroblastic tumors
- Other cancers where ALK rearrangements are suspected
Symptoms That May Warrant Testing
- Persistent cough or coughing up blood
- Shortness of breath or chest pain
- Unexplained weight loss and fatigue
- Recurrent respiratory infections
- Enlarged lymph nodes or masses
Benefits of Taking the ALK D5F3 Test
Undergoing the ALK D5F3 Immunohistochemistry Test offers numerous advantages for cancer patients and their healthcare providers:
Personalized Treatment Planning
The test results directly influence treatment decisions, enabling oncologists to prescribe targeted therapies specifically designed to inhibit ALK-driven cancer growth. This personalized approach often leads to better outcomes with fewer side effects compared to traditional chemotherapy.
Improved Survival Rates
Patients with ALK-positive cancers who receive appropriate targeted therapy typically experience significantly improved progression-free survival and overall survival rates. Early identification of ALK status ensures timely access to these life-extending treatments.
Cost-Effective Diagnostic Approach
At only $162, the ALK D5F3 test provides exceptional value by potentially avoiding ineffective treatments and directing resources toward therapies with higher success probabilities.
Comprehensive Cancer Profiling
The test contributes to a complete molecular profile of the tumor, which may be combined with other biomarker testing to develop the most effective treatment strategy.
Understanding Your Test Results
Interpretation Guidelines
Your ALK D5F3 test results will typically fall into one of these categories:
ALK-Positive Result
A positive result indicates the presence of ALK protein overexpression, suggesting ALK gene rearrangement. This finding qualifies patients for ALK inhibitor targeted therapies, which have shown remarkable effectiveness in controlling ALK-positive cancers.
ALK-Negative Result
A negative result means no significant ALK protein expression was detected. While this excludes ALK-targeted therapy options, it helps direct attention toward other potential treatment avenues and biomarker testing.
Equivocal or Borderline Results
In some cases, results may be unclear or borderline. Your oncologist may recommend additional testing, such as FISH (fluorescence in situ hybridization) or next-generation sequencing, to confirm the ALK status.
Next Steps After Testing
- Discuss results thoroughly with your oncology team
- Consider all available treatment options based on the findings
- Explore clinical trial opportunities if appropriate
- Develop a comprehensive care plan addressing your specific cancer type
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| ALK D5F3 Immunohistochemistry Test | $162 USD | $238 USD |
Sample Requirements and Processing
Sample Collection
For accurate ALK D5F3 testing, please provide:
- Tumor tissue preserved in 10% formal-saline solution
- Formalin-fixed paraffin-embedded tissue blocks
- Ship samples at room temperature with proper packaging
Required Documentation
- Complete histopathology report
- Specific biopsy site information
- Detailed clinical history and symptoms
- Previous treatment information if applicable
Turnaround Times
- Standard tissue biopsy: 5 days
- Large complex tissue samples: 7 days
- Daily sample acceptance until 6:00 PM
Nationwide Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified laboratories ensures consistent, high-quality results regardless of your location.
Take Action Today
Don’t delay critical cancer diagnosis and treatment planning. The ALK D5F3 Immunohistochemistry Test provides essential information that could significantly impact your treatment journey and overall outcomes. Our experienced team is ready to assist you with scheduling, sample collection guidance, and result interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to book your ALK D5F3 test and take the first step toward personalized cancer care.
Early molecular profiling through tests like the ALK D5F3 Immunohistochemistry can make a substantial difference in cancer treatment success. Trust our expertise in molecular diagnostics to provide the accurate, timely information you need for informed medical decisions.
