HOXD13 Gene Syndactyly Type 5 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Limb Development Disorders
The HOXD13 Gene Syndactyly Type 5 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for congenital limb abnormalities. This advanced testing method provides crucial insights into the genetic basis of Syndactyly Type 5, enabling accurate diagnosis and informed medical decision-making for affected individuals and families.
What is HOXD13 Gene Syndactyly Type 5?
Syndactyly Type 5 is a rare genetic condition characterized by the fusion of fingers and toes, specifically affecting the middle and ring fingers. This autosomal dominant disorder results from mutations in the HOXD13 gene, which plays a critical role in limb development during embryonic growth. The HOXD13 gene provides instructions for producing a protein that regulates the development of hands and feet, and mutations disrupt normal digit formation.
What This Test Measures and Detects
Our comprehensive NGS-based genetic test specifically analyzes:
- Complete sequencing of the HOXD13 gene to identify pathogenic variants
- Detection of point mutations, insertions, and deletions affecting gene function
- Assessment of polyalanine tract expansions, a common mutation type in this condition
- Evaluation of genetic variations that disrupt normal limb patterning
The test utilizes state-of-the-art Next-Generation Sequencing technology, providing unparalleled accuracy in detecting even subtle genetic changes that conventional methods might miss.
Who Should Consider This Genetic Test?
Clinical Indications and Symptoms
This test is recommended for individuals presenting with:
- Unexplained fusion of fingers or toes, particularly between digits 3 and 4
- Family history of syndactyly or hand/foot abnormalities
- Congenital limb malformations without clear diagnosis
- Planning pregnancy with known family history of limb abnormalities
- Unexplained developmental delays involving extremities
- Multiple family members with similar hand or foot anomalies
Significant Benefits of HOXD13 Genetic Testing
Medical and Personal Advantages
Undergoing HOXD13 genetic testing provides numerous benefits:
- Accurate Diagnosis: Confirms or rules out Syndactyly Type 5 with precision
- Family Planning Guidance: Enables informed reproductive decisions
- Treatment Planning: Guides surgical interventions and management strategies
- Genetic Counseling: Provides comprehensive risk assessment for family members
- Early Intervention: Facilitates timely medical and therapeutic interventions
- Peace of Mind: Reduces uncertainty about genetic inheritance patterns
Understanding Your Test Results
Interpreting Genetic Findings
Your test results will be thoroughly explained during your genetic counseling session:
- Positive Result: Indicates a detected mutation in the HOXD13 gene, confirming diagnosis
- Negative Result: Suggests no mutation detected, though other genetic causes may exist
- Variant of Uncertain Significance: Requires additional family studies for interpretation
- Carrier Status: Important for family members and future generations
Our genetic counselors provide comprehensive guidance on result implications, inheritance patterns, and next steps for medical management.
Test Pricing and Sample Requirements
| Test Component | Details |
|---|---|
| Test Name | HOXD13 Gene Syndactyly Type 5 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Pre-test Requirements | Clinical History and Genetic Counseling Session |
Nationwide Accessibility and Convenience
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and medical professionals ensures you receive the highest quality care regardless of your location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about genetic conditions affect your family’s future. Our comprehensive HOXD13 genetic testing provides the answers you need for informed medical decisions and peace of mind. Our team of genetic specialists is ready to guide you through every step of the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your HOXD13 Gene Syndactyly Type 5 NGS Genetic DNA Test. Take control of your genetic health with confidence and clarity.
