HOXD13 Gene Syndactyly Type 1 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Limb Development Disorders
The HOXD13 Gene Syndactyly Type 1 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for congenital limb abnormalities. This advanced molecular test specifically targets mutations in the HOXD13 gene, which plays a critical role in embryonic development of hands and feet. Syndactyly Type 1, also known as zygodactyly, is characterized by the fusion of fingers or toes, typically affecting the third and fourth digits. Our state-of-the-art Next-Generation Sequencing technology provides unparalleled accuracy in detecting genetic variations that contribute to this condition.
What This Test Measures and Detects
This comprehensive genetic analysis examines the HOXD13 gene for specific mutations and variations that disrupt normal limb development. The test identifies:
- Point mutations in the HOXD13 gene coding regions
- Insertions and deletions affecting gene function
- Polymorphisms associated with syndactyly phenotypes
- Genetic variations that impact protein-DNA binding
- Mutations affecting homeobox domain functionality
The HOXD13 gene encodes a transcription factor essential for proper patterning of developing limbs during embryogenesis. Mutations in this gene disrupt the normal separation of digits, leading to the characteristic fused appearance seen in Syndactyly Type 1.
Who Should Consider This Genetic Test
This test is recommended for individuals and families experiencing:
- Congenital fusion of fingers or toes, particularly between digits 3 and 4
- Family history of syndactyly or limb abnormalities
- Planning pregnancy with known genetic risk factors
- Unexplained hand or foot malformations in newborns
- Multiple family members affected by similar limb conditions
- Individuals with syndactyly seeking genetic confirmation
Clinical Benefits of HOXD13 Genetic Testing
Undergoing HOXD13 genetic testing provides numerous advantages for patients and families:
- Accurate Diagnosis: Confirms genetic basis of syndactyly symptoms
- Family Planning Guidance: Helps assess inheritance risks for future pregnancies
- Surgical Planning: Informs timing and approach for separation procedures
- Genetic Counseling: Provides comprehensive understanding of inheritance patterns
- Early Intervention: Enables proactive management and treatment planning
- Psychological Relief: Reduces uncertainty about condition cause and progression
Understanding Your Test Results
Our genetic counseling team provides detailed interpretation of your HOXD13 test results:
- Positive Result: Indicates presence of HOXD13 mutation associated with Syndactyly Type 1
- Negative Result: Suggests syndactyly may have other genetic or environmental causes
- Variant of Uncertain Significance: Requires additional family studies for interpretation
- Carrier Status: Important for family planning and genetic counseling
All results include comprehensive genetic counseling to help you understand implications for your health and family.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| HOXD13 Gene Syndactyly Type 1 NGS Genetic DNA Test | $500 USD | $700 USD |
Nationwide Testing Availability
We have genetic testing facilities conveniently located across the United States, including major metropolitan areas such as New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and medical professionals ensures you receive comprehensive care regardless of your location.
Take the Next Step Toward Genetic Clarity
If you or your family members are experiencing symptoms of syndactyly or have concerns about genetic inheritance patterns, our HOXD13 genetic test provides the answers you need. Our team of genetic specialists is ready to guide you through the testing process and help you understand your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your HOXD13 Gene Syndactyly Type 1 NGS Genetic DNA Test. Take control of your genetic health with accurate, reliable testing from America’s leading genetics laboratory.
