Hereditary Spastic Paraplegia Gene Panel
Comprehensive Genetic Testing for Hereditary Spastic Paraplegia
The Hereditary Spastic Paraplegia Gene Panel represents a cutting-edge diagnostic tool designed to identify genetic mutations responsible for hereditary spastic paraplegia (HSP), a group of inherited neurological disorders characterized by progressive stiffness and weakness in the lower limbs. This comprehensive genetic analysis provides crucial insights for patients and healthcare providers seeking accurate diagnosis and personalized management strategies for this complex condition.
What Does This Test Measure?
Our advanced Hereditary Spastic Paraplegia Gene Panel utilizes next-generation sequencing (NGS) technology to analyze multiple genes associated with various forms of HSP. The test specifically detects:
- Mutations in SPG genes (SPAST, ATL1, REEP1, and others)
- Pathogenic variants affecting upper motor neuron function
- Genetic abnormalities causing progressive corticospinal tract degeneration
- Inherited mutations leading to progressive spasticity and weakness
- Both autosomal dominant and recessive forms of HSP
Who Should Consider This Test?
This genetic panel is particularly recommended for individuals experiencing:
- Progressive difficulty walking or gait abnormalities
- Unexplained muscle stiffness in the legs
- Family history of hereditary spastic paraplegia
- Progressive lower limb weakness without clear cause
- Early-onset spasticity in childhood or young adulthood
- Planning for family with known HSP risk factors
- Seeking genetic counseling for neurological symptoms
Key Benefits of Genetic Testing for HSP
Undergoing the Hereditary Spastic Paraplegia Gene Panel offers numerous advantages:
- Accurate Diagnosis: Provides definitive genetic confirmation of HSP subtype
- Personalized Treatment: Enables targeted management strategies based on specific genetic findings
- Family Planning: Offers crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates timely implementation of physical therapy and supportive care
- Prognostic Information: Helps predict disease progression and potential complications
- Research Contribution: Advances understanding of HSP genetics and potential therapies
Understanding Your Test Results
Our comprehensive genetic analysis provides detailed insights into your HSP status:
- Positive Result: Identifies specific genetic mutations confirming HSP diagnosis
- Negative Result: No pathogenic variants detected in tested genes
- Variant of Uncertain Significance: Genetic changes with unclear clinical implications
- Carrier Status: Identifies individuals carrying recessive HSP mutations
All results include detailed interpretation by our genetic specialists and recommendations for next steps, including potential treatment options, lifestyle modifications, and family testing considerations.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | Hereditary Spastic Paraplegia Gene Panel |
| Discount Price | $900 USD |
| Regular Price | $1200 USD |
| Turnaround Time | 4-6 weeks |
| Sample Type | Amniotic fluid / Chorionic villi / Peripheral blood |
| Test Components | Sterile container / Sterile Normal Saline Container / EDTA Vacutainer |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States with convenient locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Book Your Test Today
Take the first step toward understanding your genetic health. Our experienced genetic counselors and healthcare professionals are ready to assist you with comprehensive testing and personalized care. Contact us today to schedule your Hereditary Spastic Paraplegia Gene Panel and gain valuable insights into your neurological health.
Call or WhatsApp: +1(267) 388-9828
Note: This test requires a doctor’s prescription for most cases. Prescription requirements may vary for surgical cases, pregnancy-related testing, or international travel purposes. Consult with your healthcare provider to determine if this test is appropriate for your specific situation.
