GRHL3 Gene Van der Woude Syndrome Type 2 NGS Genetic DNA Test
Comprehensive Genetic Testing for Craniofacial Disorders
The GRHL3 Gene Van der Woude Syndrome Type 2 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for congenital facial abnormalities. This specialized test utilizes cutting-edge Next-Generation Sequencing (NGS) technology to analyze the GRHL3 gene, which plays a critical role in embryonic facial development. Van der Woude Syndrome Type 2 is an autosomal dominant genetic disorder characterized by distinctive facial features, making early and accurate diagnosis essential for proper medical management and family planning.
What Does This Test Detect?
Our advanced NGS genetic test specifically targets and identifies mutations in the GRHL3 (Grainyhead-like transcription factor 3) gene. This comprehensive analysis detects:
- Point mutations and single nucleotide variants in the GRHL3 gene
- Small insertions and deletions affecting gene function
- Pathogenic variants associated with Van der Woude Syndrome Type 2
- Genetic markers for autosomal dominant inheritance patterns
- Specific mutations linked to congenital lip pits and cleft anomalies
Who Should Consider This Genetic Test?
Clinical Indications and Symptoms
This genetic test is recommended for individuals presenting with:
- Congenital cleft lip and/or cleft palate
- Characteristic paramedian lower lip pits
- Family history of Van der Woude Syndrome
- Unexplained craniofacial abnormalities
- Multiple family members with cleft lip/palate disorders
- Parents planning pregnancy with family history of facial clefts
- Individuals with suspected genetic syndromes involving facial development
Benefits of GRHL3 Genetic Testing
Undergoing the GRHL3 Gene Van der Woude Syndrome Type 2 test provides numerous advantages:
- Definitive Diagnosis: Confirms or rules out Van der Woude Syndrome Type 2 with high accuracy
- Family Planning Guidance: Provides essential information for genetic counseling and reproductive decisions
- Early Intervention: Enables timely medical and surgical management of affected individuals
- Hereditary Risk Assessment: Identifies inheritance patterns for family members
- Comprehensive Care Planning: Supports multidisciplinary treatment approaches
- Psychological Relief: Reduces uncertainty and provides clarity about genetic conditions
Understanding Your Test Results
Our genetic specialists provide comprehensive interpretation of your GRHL3 gene analysis:
- Positive Result: Indicates the presence of a pathogenic GRHL3 mutation, confirming Van der Woude Syndrome Type 2 diagnosis
- Negative Result: Suggests absence of detectable GRHL3 mutations, though other genetic causes should be considered
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Determines if individuals carry the mutation without showing symptoms
All results include detailed genetic counseling to help you understand the implications for your health and family.
Test Details and Pricing
| Test Feature | Details |
|---|---|
| Test Name | GRHL3 Gene Van der Woude Syndrome Type 2 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
To ensure accurate results, we require:
- Complete clinical history of the patient
- Genetic counseling session to create a detailed family pedigree
- Documentation of affected family members
- Informed consent for genetic testing
Nationwide Availability
We have specialized genetic testing centers across the United States, including locations in New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and all major metropolitan areas. Our network of certified genetic counselors and medical professionals ensures you receive comprehensive care regardless of your location.
Book Your Genetic Test Today
Take the first step toward understanding your genetic health. Our expert team is ready to guide you through the testing process and provide the answers you need for informed healthcare decisions.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your GRHL3 genetic test and receive professional genetic counseling.
Don’t let uncertainty about genetic conditions affect your family’s future. Our advanced NGS technology and expert genetic analysis provide the clarity you need for proper medical management and family planning.
