Glucose-6-Phosphate Dehydrogenase (G6PD) Full Length Gene Sequence Analysis
Understanding G6PD Genetic Testing
The Glucose-6-Phosphate Dehydrogenase (G6PD) Full Length Gene Sequence Analysis represents a cutting-edge approach to diagnosing G6PD deficiency, one of the most common enzyme deficiencies worldwide affecting over 400 million people globally. This comprehensive genetic examination provides unparalleled insights into your genetic makeup, enabling precise identification of mutations within the G6PD gene located on the X chromosome.
What Does This Test Measure?
This advanced diagnostic test employs Sanger sequencing methodology to analyze the complete coding region of the G6PD gene, spanning approximately 13 kilobases. The test specifically detects:
- Point mutations affecting enzyme function
- Small insertions and deletions disrupting gene expression
- Genetic variants associated with varying degrees of enzyme deficiency
- Mutations affecting protein structure and catalytic activity
- Genetic markers predicting disease severity and clinical manifestations
Who Should Consider G6PD Genetic Testing?
This comprehensive genetic analysis is recommended for individuals experiencing:
- Unexplained episodes of hemolytic anemia following medication exposure
- Family history of G6PD deficiency or related hemolytic disorders
- Neonatal jaundice without clear underlying cause
- Planned use of medications known to trigger hemolysis in G6PD-deficient individuals
- Recurrent anemia episodes following infection or stress
- Individuals from ethnic backgrounds with high G6PD deficiency prevalence
- Pre-surgical screening for anesthesia risk assessment
Clinical Indications and Symptoms
Patients presenting with symptoms including dark urine, fatigue, rapid heart rate, shortness of breath, abdominal pain, or jaundice following exposure to oxidative stressors should consider this genetic evaluation. The test is particularly valuable for individuals planning international travel to malaria-endemic regions where antimalarial medications may be required.
Benefits of G6PD Full Gene Sequence Analysis
- Precise Diagnosis: Provides definitive genetic confirmation of G6PD deficiency
- Personalized Medicine: Enables tailored medication and treatment plans
- Preventive Care: Identifies triggers to avoid future hemolytic crises
- Family Planning: Offers genetic counseling for inheritance patterns
- Comprehensive Assessment: Detects both common and rare genetic variants
- Long-term Management: Supports ongoing healthcare decision-making
Understanding Your Test Results
Your G6PD genetic test results will provide detailed information about specific mutations identified in your G6PD gene. Results typically fall into several categories:
Normal Results
No pathogenic mutations detected indicates normal G6PD enzyme function. However, clinical correlation with enzyme activity levels may be recommended for comprehensive assessment.
Pathogenic Variants
Identification of known disease-causing mutations confirms G6PD deficiency diagnosis. The specific mutation identified can provide insights into expected clinical severity and management requirements.
Variants of Uncertain Significance
Some genetic changes may have unknown clinical significance. In such cases, additional family studies or functional testing may be recommended to determine clinical relevance.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | Glucose-6-Phosphate Dehydrogenase (G6PD) Full Length Gene Sequence Analysis |
| Discount Price | $938 USD |
| Regular Price | $1,250 USD |
| Turnaround Time | 2-3 weeks |
| Sample Type | Peripheral blood / Amniotic Fluid / Chorionic villi / Cord blood |
| Testing Method | Sanger Sequencing |
| Test Components | Sterile container / Sterile Normal Saline Container / EDTA Vacutainer (2ml) |
Pre-Test Instructions
The Glucose-6-Phosphate Dehydrogenase (G6PD) full length gene sequence analysis requires a Doctor’s prescription for most cases. However, prescription requirements do not apply for surgical preparation, pregnancy-related testing, or individuals planning international travel. Our genetic counselors are available to discuss testing indications and provide comprehensive pre-test education.
Nationwide Testing Availability
We provide comprehensive genetic testing services across all major cities in the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, San Francisco, and many more locations. Our network of certified collection centers ensures convenient access to this advanced genetic testing.
Book Your G6PD Genetic Test Today
Take control of your genetic health with our comprehensive G6PD full gene sequence analysis. Our team of genetic specialists and certified phlebotomists are ready to assist you with convenient scheduling and professional sample collection. For appointments, genetic counseling, or additional information about this vital genetic test, contact our dedicated healthcare team.
Call or WhatsApp: +1(267) 388-9828
Schedule your appointment today to receive the definitive genetic insights needed for personalized medical management and preventive healthcare planning. Our commitment to excellence in genetic testing ensures you receive accurate, reliable results with comprehensive clinical interpretation and ongoing support.
